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Best Claude skills for science

Science skills give agents domain tools for biology, chemistry, genomics and physics: database lookups, analysis pipelines and lab workflows. K-Dense's scientific-agent-skills and Google DeepMind's science-skills are the largest collections.

216 science skills · ranked live · November 2026

The top 10. Ranked by the Alyn Score.

  1. GitHub

    Awesome Copilot

    #1
    GitHub

    Arize Evaluator

    Handles LLM-as-judge evaluation workflows on Arize including creating/updating evaluators, running evaluations on spans or experiments, managing tasks, trigger-run operations, column…

    Pack41k2.4MScore 85
    Details
  2. GitHub

    Awesome Copilot

    #2
    GitHub

    Arize Experiment

    Creates, runs, and analyzes Arize experiments for evaluating and comparing model performance. Covers experiment CRUD, exporting runs, comparing results, and evaluation workflows using the…

    Pack41k2.4MScore 85
    Details
  3. #3
    JuliusBrussee

    Caveman Manage

    Inspect Caveman Cloud's experiment lifecycle and block unsafe execution. Use when asked to start, approve, cancel, promote or roll back a Caveman experiment.

    Pack119k4.8MScore 85
    Details
  4. K-Dense

    Scientific Agent Skills

    #4
    K-Dense

    Alphagenome

    Looks up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq…

    Pack57k328kScore 84
    Details
  5. K-Dense

    Scientific Agent Skills

    #5
    K-Dense

    Analytical Method Validation

    Plans, executes, and documents validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP //, ICH M10 bioanalytical, CLSI EP, or…

    Pack57k328kScore 84
    Details
  6. K-Dense

    Scientific Agent Skills

    #6
    K-Dense

    Arbor

    Applies Arbor Hypothesis Tree Refinement to research artifacts with repeatable evaluators, including model training, agent harnesses, data synthesis and benchmark optimization. Uses…

    Pack57k328kScore 84
    Details
  7. #7
    Yuan1z0825

    Nature Paper Card

    Build a structured deep-reading Paper Card for one scientific paper, analysing methods, experiment-to-claim evidence, limitations, and research ideas. Use for 论文精读卡、方法拆解、证据链分析; not…

    Pack53k301kScore 84
    Details
  8. sickn33

    Agentic Awesome Skills

    #8
    sickn33

    Ab Testing

    When the user wants to plan, design, or implement an A/B test or experiment, or build a growth experimentation program.

    Pack49k584kScore 83
    Details
  9. #9
    Yuan1z0825

    Nature Social Science

    社会科学及相邻学科学术写作与选题论证工作台,覆盖选题构思、文献梳理、论证组织、学术表达四大要素。Use for 找论文题目/研究问题、把兴趣或宽泛主题变成可讨论的研究方向、文献综述与领域版图、区分"研究少"与真正未决的知识问题、设计证据路线与主张边界、新颖性审计与"审稿人2"式攻击、博士/论文可行性评估、导师沟通话术、或检查论文中的过度断…

    Pack53k301kScore 82
    Details
  10. #10
    Yuan1z0825

    Nature Writing

    Draft or restructure scientific manuscript arguments, sections, and initial-submission materials from author-provided evidence. Use for 论文写作、章节起草、论证重构、正文压缩、首次投稿材料. Use nature-polishing for…

    Pack53k301kScore 82
    Details

What makes a great science skill.

  • Pinned, real libraries and databases with usage examples.

  • Validation steps that catch silent errors in pipelines.

  • Clear licensing for data sources.

All 216 science skills.

GitHub

Awesome Copilot

85
GitHub

arize-evaluator

Handles LLM-as-judge evaluation workflows on Arize including creating/updating evaluators, running evaluations on spans or experiments, managing tasks, trigger-run operations, column…

Pack41k2.4MAI engineering

GitHub

Awesome Copilot

85
GitHub

arize-experiment

Creates, runs, and analyzes Arize experiments for evaluating and comparing model performance. Covers experiment CRUD, exporting runs, comparing results, and evaluation workflows using the…

Pack41k2.4MScience
85
JuliusBrussee

caveman-manage

Inspect Caveman Cloud's experiment lifecycle and block unsafe execution. Use when asked to start, approve, cancel, promote or roll back a Caveman experiment.

Pack119k4.8MCoding

K-Dense

Scientific Agent Skills

84
K-Dense

alphagenome

Looks up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq…

Pack57k328kScience

K-Dense

Scientific Agent Skills

84
K-Dense

analytical-method-validation

Plans, executes, and documents validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP //, ICH M10 bioanalytical, CLSI EP, or…

Pack57k328kScience

K-Dense

Scientific Agent Skills

84
K-Dense

arbor

Applies Arbor Hypothesis Tree Refinement to research artifacts with repeatable evaluators, including model training, agent harnesses, data synthesis and benchmark optimization. Uses…

Pack57k328kScience
84
Yuan1z0825

nature-paper-card

Build a structured deep-reading Paper Card for one scientific paper, analysing methods, experiment-to-claim evidence, limitations, and research ideas. Use for 论文精读卡、方法拆解、证据链分析; not…

Pack53k301kResearch

sickn33

Agentic Awesome Skills

83
sickn33

ab-testing

When the user wants to plan, design, or implement an A/B test or experiment, or build a growth experimentation program.

Pack49k584kTesting
82
Yuan1z0825

nature-social-science

社会科学及相邻学科学术写作与选题论证工作台,覆盖选题构思、文献梳理、论证组织、学术表达四大要素。Use for 找论文题目/研究问题、把兴趣或宽泛主题变成可讨论的研究方向、文献综述与领域版图、区分"研究少"与真正未决的知识问题、设计证据路线与主张边界、新颖性审计与"审稿人2"式攻击、博士/论文可行性评估、导师沟通话术、或检查论文中的过度断…

Pack53k301kScience
82
Yuan1z0825

nature-writing

Draft or restructure scientific manuscript arguments, sections, and initial-submission materials from author-provided evidence. Use for 论文写作、章节起草、论证重构、正文压缩、首次投稿材料. Use nature-polishing for…

Pack53k301kWriting

Jeffallan

Claude Skills

77
Jeffallan

chaos-engineer

Designs chaos experiments, creates failure injection frameworks, and facilitates game day exercises for distributed systems — producing runbooks, experiment manifests, rollback procedures…

Pack12k457kCoding
77
gamedev-skills

physics-tuning

Tune game physics for stable, good-feeling motion — fixed vs variable timestep, render interpolation, mass/gravity/drag, continuous collision detection (CCD) to stop tunneling, fixing…

Pack8.2k749kScience

Expo

Skills

75
Expo

expo-migrate-module

Migrate an existing Apple/Swift Expo native module from the Expo Modules API 1.0 definition DSL to the 2.0 macro API (sometimes called v2) while preserving its JavaScript and TypeScript…

Pack4.1k1.1MMobile

wanshuiyin

Auto Claude Code Research In Sleep

74
wanshuiyin

experiment-queue

SSH job queue for multi-seed/multi-config ML experiments with OOM-aware retry, stale-screen cleanup, and wave-transition race prevention. Use when user says "batch experiments", "队列实验"…

Pack19k42kScience
73
phuryn

brainstorm-experiments-existing

Design experiments to test assumptions for an existing product — prototypes, A/B tests, spikes, and other low-effort validation methods. Use when validating assumptions, testing feature…

Pack28k245kProduct management
73
phuryn

brainstorm-experiments-new

Design lean startup experiments (pretotypes) for a new product. Creates XYZ hypotheses and suggests low-effort validation methods like landing pages, explainer videos, and pre-orders. Use…

Pack28k245kProduct management

NVIDIA

Skills

73
NVIDIA

complexa-target

Add, edit, inspect, or validate Proteina-Complexa target definitions for protein binders, ligand binders, and AME motif scaffolding. Use for target registries, chain/residue selectors…

Pack3.9k429kScience

NVIDIA

Skills

73
NVIDIA

genomics-workflow-acceleration

Use when accelerating existing genomics workflows with NVIDIA Parabricks, improving runtime or price/performance, converting pipeline steps to GPUs, or comparing CPU and GPU workflow…

Pack3.9k429kAutomation

Google DeepMind

Science Skills

72
Google DeepMind

alphagenome-single-variant-analysis

Analyzes genetic variant effects on gene expression (RNA-seq), chromatin accessibility (DNASE), histone marks (ChIP), and transcription factors using the AlphaGenome API. Use when the user…

Pack3.4k91kScience

NVIDIA

Skills

72
NVIDIA

boltz2-nim

Use Boltz2 NIM for biomolecular structure prediction and binding affinity. Invoke for Boltz2, protein structures, protein-ligand/DNA/RNA complexes, SMILES or CCD ligands, pIC50/IC50…

Pack3.9k429kDevOps

Google DeepMind

Science Skills

72
Google DeepMind

chembl-database

Query the ChEMBL database for bioactive molecules, drug targets, bioactivity data, approved drugs, and chemical structures. Use when the user asks about compounds, targets, IC50/Ki values…

Pack3.4k91kBackend

Google DeepMind

Science Skills

72
Google DeepMind

clinical-trials-database

Query ClinicalTrials.gov via APIv2. Use when you want to search for trials by condition, drug, location, status, or phase; retrieve trial details by NCT ID; check eligibility/inclusion…

Pack3.4k91kScience

wanshuiyin

Auto Claude Code Research In Sleep

72
wanshuiyin

experiment-audit

Audit experiment integrity before claiming results. Uses cross-model review (external reviewer backend) to check for fake ground truth, score normalization fraud, phantom results, and…

Pack19k42kScience

wanshuiyin

Auto Claude Code Research In Sleep

72
wanshuiyin

experiment-bridge

Workflow 1.5: Bridge between idea discovery and auto review. Reads EXPERIMENT_PLAN.md, implements experiment code, deploys to GPU, collects initial results. Use when user says "实现实验"…

Pack19k42kScience

alirezarezvani

Claude Skills

71
alirezarezvani

chaos-experiment

Pack30k240kScience

Hugging Face

Skills

71
Hugging Face

huggingface-trackio

Track and visualize ML training experiments with Trackio. Use when logging metrics during training (Python API), firing alerts for training diagnostics, or retrieving/analyzing logged…

Pack11k42kAI engineering

aaron-he-zhu

Aaron Marketing Skills

68
aaron-he-zhu

send-experiment-designer

Use when the user asks to "design an email A/B test", "set up a multivariate subject/CTA test", "run a send-time test", "build a hold-out group", or "is this email result statistically and…

Pack3.1k142kScience
67
jeremylongshore

abridge-performance-tuning

Measure and improve Abridge workflow latency and friction using privacy-safe health-system evidence. Use when clinicians report slow capture, note readiness, review, or EHR handoff. Trigger…

Pack2.9k57kHealthcare
64
brycewang-stanford

academic-plotting

Generates publication-quality figures for ML papers from research context. Given a paper section or description, extracts system components and relationships to generate architecture…

Pack5k2kResearch
64
brycewang-stanford

autoresearch

Orchestrates end-to-end autonomous AI research projects using a two-loop architecture. The inner loop runs rapid experiment iterations with clear optimization targets. The outer loop…

Pack5k2kResearch
64
foryourhealth111-pixel

chembl-database

Query ChEMBL bioactive molecules and drug discovery data. Search compounds by structure/properties, retrieve bioactivity data (IC50, Ki), find inhibitors, perform SAR studies, for medicinal…

Pack3.8k950Backend
64
foryourhealth111-pixel

clinical-decision-support

Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified with outcomes) and…

Pack3.8k950Healthcare
64
foryourhealth111-pixel

clinical-reports

Write comprehensive clinical reports including case reports (CARE guidelines), diagnostic reports (radiology/pathology/lab), clinical trial reports (ICH-E3, SAE, CSR), and patient…

Pack3.8k950Science
64
brycewang-stanford

hypothesis-generation

Structured hypothesis formulation from observations. Use when you have experimental observations or data and need to formulate testable hypotheses with predictions, propose mechanisms, and…

Pack5k2kScience

GarethManning

Education Agent Skills

61
GarethManning

adaptive-hint-sequence-designer

Generate a cascading hint sequence for a problem type, revealing progressively without giving answers. Use when designing tutoring dialogues or scaffolded worksheets.

Pack97225kEducation
61
glebis

agency-docs-updater

End-to-end pipeline for publishing Claude Code lab meetings. Accepts optional args: date (YYYYMMDD, "yesterday", "today") and lab number (e.g. "04"). Examples: "yesterday 04", "20260420…

Pack41315kScience

Science skills, explained.

Also searched as: scientific agent skills, bioinformatics skill, ai scientist skills, deepmind science skills.

What are the best Claude skills for science?

Right now the top-ranked science skills on Alyn are Arize Evaluator (GitHub), Arize Experiment (GitHub), Caveman Manage (JuliusBrussee). Rankings combine GitHub stars, installs, freshness and depth, and update live.

Are there official DeepMind skills?

Yes. google-deepmind/science-skills is published by Google DeepMind for agentic scientific workflows.

Do science skills replace domain review?

No. They speed up analysis; results still need expert review.

How do I install a science skill?

Run npx skills add owner/repo in your project, or copy the folder with SKILL.md into ~/.claude/skills. Every skill on this page has a ready-to-copy command.

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