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Best Claude skills for science

Science skills give agents domain tools for biology, chemistry, genomics and physics: database lookups, analysis pipelines and lab workflows. K-Dense's scientific-agent-skills and Google DeepMind's science-skills are the largest collections.

216 science skills · ranked live · November 2026

The top 10. Ranked by the Alyn Score.

  1. GitHub

    Awesome Copilot

    #1
    GitHub

    Arize Evaluator

    Handles LLM-as-judge evaluation workflows on Arize including creating/updating evaluators, running evaluations on spans or experiments, managing tasks, trigger-run operations, column…

    Pack41k2.4MScore 85
    Details
  2. GitHub

    Awesome Copilot

    #2
    GitHub

    Arize Experiment

    Creates, runs, and analyzes Arize experiments for evaluating and comparing model performance. Covers experiment CRUD, exporting runs, comparing results, and evaluation workflows using the…

    Pack41k2.4MScore 85
    Details
  3. #3
    JuliusBrussee

    Caveman Manage

    Inspect Caveman Cloud's experiment lifecycle and block unsafe execution. Use when asked to start, approve, cancel, promote or roll back a Caveman experiment.

    Pack119k4.8MScore 85
    Details
  4. K-Dense

    Scientific Agent Skills

    #4
    K-Dense

    Alphagenome

    Looks up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq…

    Pack57k328kScore 84
    Details
  5. K-Dense

    Scientific Agent Skills

    #5
    K-Dense

    Analytical Method Validation

    Plans, executes, and documents validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP //, ICH M10 bioanalytical, CLSI EP, or…

    Pack57k328kScore 84
    Details
  6. K-Dense

    Scientific Agent Skills

    #6
    K-Dense

    Arbor

    Applies Arbor Hypothesis Tree Refinement to research artifacts with repeatable evaluators, including model training, agent harnesses, data synthesis and benchmark optimization. Uses…

    Pack57k328kScore 84
    Details
  7. #7
    Yuan1z0825

    Nature Paper Card

    Build a structured deep-reading Paper Card for one scientific paper, analysing methods, experiment-to-claim evidence, limitations, and research ideas. Use for 论文精读卡、方法拆解、证据链分析; not…

    Pack53k301kScore 84
    Details
  8. sickn33

    Agentic Awesome Skills

    #8
    sickn33

    Ab Testing

    When the user wants to plan, design, or implement an A/B test or experiment, or build a growth experimentation program.

    Pack49k584kScore 83
    Details
  9. #9
    Yuan1z0825

    Nature Social Science

    社会科学及相邻学科学术写作与选题论证工作台,覆盖选题构思、文献梳理、论证组织、学术表达四大要素。Use for 找论文题目/研究问题、把兴趣或宽泛主题变成可讨论的研究方向、文献综述与领域版图、区分"研究少"与真正未决的知识问题、设计证据路线与主张边界、新颖性审计与"审稿人2"式攻击、博士/论文可行性评估、导师沟通话术、或检查论文中的过度断…

    Pack53k301kScore 82
    Details
  10. #10
    Yuan1z0825

    Nature Writing

    Draft or restructure scientific manuscript arguments, sections, and initial-submission materials from author-provided evidence. Use for 论文写作、章节起草、论证重构、正文压缩、首次投稿材料. Use nature-polishing for…

    Pack53k301kScore 82
    Details

What makes a great science skill.

  • Pinned, real libraries and databases with usage examples.

  • Validation steps that catch silent errors in pipelines.

  • Clear licensing for data sources.

All 216 science skills.

GarethManning

Education Agent Skills

61
GarethManning

ai-facilitated-collaborative-learning-designer

Design AI-supported collaborative tasks that structure group interaction and address participation problems. Use when students struggle to collaborate effectively on group tasks.

Pack97225kEducation

GarethManning

Education Agent Skills

61
GarethManning

ai-feedback-design-principles

Audit and redesign AI-generated feedback for pedagogical quality, timing, and learning impact. Use when building or reviewing automated feedback in digital learning tools.

Pack97225kEducation

product-on-purpose

Pm Skills

61
product-on-purpose

define-hypothesis

Defines a testable hypothesis with clear success metrics and a validation approach. Use when forming assumptions to test or aligning a team on what success looks like, before any experiment…

Pack79651kDesign

posit-dev

Skills

60
posit-dev

r-lifecycle

Guidance for managing R package lifecycle according to tidyverse principles using the lifecycle package. Use when: (1) Setting up lifecycle infrastructure in a package, (2) Deprecating…

Pack56320kScience

databricks

Databricks Agent Skills

59
databricks

spark-python-data-source

Build custom Python data sources for Apache Spark using the PySpark DataSource API — batch and streaming readers/writers for external systems. Use this skill whenever someone wants to…

Pack39417kResearch

LeoYeAI

Agent Master Skills

58
LeoYeAI

ab-testing

When the user wants to plan, design, or implement an A/B test or experiment, or build a growth experimentation program. Also use when the user mentions "A/B test," "split test,"…

Pack2.2k499Testing
58
jaechang-hits

molecular-visualization-3dmol

3Dmol.js WebGL molecular visualization emitted as self-contained HTML. Render structures (PDB/SDF/XYZ/MOL2/cube) with stick, sphere, cartoon, line, and surface styles; animate trajectories…

Pack38713kScience

benchflow-ai

Skillsbench

58
benchflow-ai

pubchem-database

Query PubChem via PUG-REST API/PubChemPy (110M+ compounds). Search by name/CID/SMILES, retrieve properties, similarity/substructure searches, bioactivity, for cheminformatics.

Pack1.9k159Backend
58
jaechang-hits

pymc-bayesian-modeling

Bayesian modeling with PyMC 5: priors, likelihood, NUTS/ADVI sampling, diagnostics (R-hat, ESS), LOO/WAIC comparison, prediction. Hierarchical, logistic, GP variants; predictive checks.

Pack38713kAI engineering

benchflow-ai

Skillsbench

58
benchflow-ai

rdkit

Cheminformatics toolkit for fine-grained molecular control. SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure search, 2D/3D generation, similarity, reactions. For…

Pack1.9k159Science
58
jaechang-hits

sciagent-skill-creator

Scaffold a new SciAgent-Skills entry. Picks pipeline/toolkit/database/guide template, creates skills/{category}/{name}/SKILL.md with valid frontmatter, appends the registry.yaml entry, runs…

Pack38713kAI engineering

quodsoler

Unreal Engine Skills

58
quodsoler

ue-physics-collision

Use when setting up collision channels and profiles, running line/sweep/overlap queries, wiring hit and overlap events, or simulating rigid bodies in Unreal Engine C++. Also use when the…

Pack44738kScience

zLanqing

Codex Claude Academic Skills

56
zLanqing

citation-management

Comprehensive citation management for academic research. Search Google Scholar and PubMed for papers, extract accurate metadata, validate citations, and generate properly formatted BibTeX…

Pack5.9k3.2kResearch

zLanqing

Codex Claude Academic Skills

56
zLanqing

exploratory-data-analysis

Perform comprehensive exploratory data analysis on scientific data files across 200+ file formats. This skill should be used when analyzing any scientific data file to understand its…

Pack5.9k3.2kScience

zLanqing

Codex Claude Academic Skills

56
zLanqing

literature-review

Conduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv, bioRxiv, Semantic Scholar, etc.). This skill should be used when conducting systematic…

Pack5.9k3.2kResearch

LeoYeAI

Agent Master Skills

56
LeoYeAI

marketing-psychology

When the user wants to apply psychological principles, mental models, or behavioral science to marketing. Also use when the user mentions 'psychology,' 'mental models,' 'cognitive bias,'…

Pack2.2k499Marketing

benchflow-ai

Skillsbench

56
benchflow-ai

pdf

PDF manipulation toolkit. Extract text/tables, create PDFs, merge/split, fill forms, for programmatic document processing and analysis.

Pack1.9k159Documents

freshtechbro

Claudedesignskills

56
freshtechbro

react-spring-physics

Physics-based animation library combining React Spring (spring dynamics, gesture integration, 60fps animations) and Popmotion (low-level composable animation utilities, reactive streams)…

Pack1.3k73kFrontend

aipoch

Medical Research Skills

56
aipoch

slide-deck-for-lab-meeting

Structures research progress into focused and actionable slides for lab meetings or project reviews without inventing missing content.

Pack2k898Research
55
GPTomics

bio-alignment-indexing

Create and use BAI/CSI indices for BAM/CRAM files using samtools and pysam. Use when enabling random access to alignment files or fetching specific genomic regions.

Pack1.2k1.3kScience
55
GPTomics

bio-alignment-pairwise

Perform pairwise sequence alignment using Biopython Bio.Align.PairwiseAligner. Use when comparing two sequences, finding optimal alignments, scoring similarity, and identifying local or…

Pack1.2k1.3kScience
55
GPTomics

bio-alignment-structural

Align protein structures using Foldseek 3Di, TM-align, US-align, DALI, or Foldmason for structural MSA. Predict, score, and superpose backbone coordinates when sequence identity is below…

Pack1.2k1.3kScience

growthenginenowoslawski

Coldoutboundskills

54
growthenginenowoslawski

experiment-design

Framework for running single-variable cold email experiments. Defines experiment types (list-only, copy-only, combined), confidence weighting, minimum sample sizes, and success criteria…

Pack8092.3kScience
54
tjboudreaux

thinking-scientific-method

When a symptom has several plausible causes, rank falsifiable hypotheses and run the cheapest discriminating observation first; prefer least-assumptive survivors only after evidence fit.

Pack1.7k20kScience
54
tjboudreaux

thinking-thought-experiment

When a real test is too rare, large, or irreversible, run a controlled counterfactual: isolate one variable, fix conditions, trace the mechanistic chain, and bound what the result implies.

Pack1.7k20kScience
52
brycewang-stanford

aaai-experiments

Use when designing or auditing AAAI experiments for the broad-AI program committee, including baselines, ablations, statistical significance, robustness, human evaluation…

Pack1.4k864Science

Jakeschincariol

Console Skill

52
Jakeschincariol

console-physics

Physics Tuner. Finds the numbers that decide how the game moves (speed, gravity, grip, jump height, frame rate) and tunes them. Scans the user's own game ELF for a float32 value stored in…

Pack366245Science
52
kwakseongjae

omd-experiment-gallery

N개 brand experiment를 한 화면에서 비교하는 gallery index.html을 생성. 각 카드는 brand name, wow rating, multi-turn refinement deltas, iframe scaled preview, standalone link 포함. '결과물 한 번에 보여줘', '갤러리 만들어'…

Pack580653Design
52
kwakseongjae

omd-lab-02-design-harness

OmD Lab #02 — 디자인 하네스 정교화 실험. 동일 task를 v1, v2, v3... 버전별 하네스 설정으로 돌려서 산출물 품질·토큰 비용·iteration 수·persona ABANDON 율을 비교. 트리거 — '/omd-lab-02', '하네스 lab 시작', '디자인 하네스 v2 돌려서 비교', 'lab #02 자동 비교'.

Pack580653Design
51
brycewang-stanford

aamas-experiments

Use when designing or auditing AAMAS experiments - self-play and population-based training, opponent selection, equilibrium and regret metrics, game-theoretic simulations, ablations, seeds…

Pack1.4k864Science
51
Microck

alphafold-database

Access AlphaFold's 200M+ AI-predicted protein structures. Retrieve structures by UniProt ID, download PDB/mmCIF files, analyze confidence metrics (pLDDT, PAE), for drug discovery and…

Pack4134.8kScience

ArtemXTech

Personal Os Skills

51
ArtemXTech

notebooklm

Turn expert podcasts into personalized protocols with cited experiments. Load 300 episodes from terminal, run an expert-informed interview, build experiments in your Obsidian morning…

Pack552159Science

staruhub

ClaudeSkills

50
staruhub

a-share-analyst

A股分析研究助手,提供行情数据获取与技术面/基本面分析框架(仅供研究参考,不构成投资建议)。适用于:(1) 获取A股行情和历史数据,(2) 技术面分析(K线形态、MACD、KDJ、RSI、布林带等),(3) 基本面分析(财务指标、估值分析),(4) 板块热点追踪,(5) 选股策略筛选与量化因子分析,(6) 生成股市分析报告。当用户询问"帮…

Pack7361.4kScience
50
brycewang-stanford

aamas-supplementary

Use when preparing AAMAS supplementary material - proofs, extended game and mechanism definitions, extra multiagent experiments, opponent-set details, and the anonymized artifact zip -…

Pack1.4k864Science
50
AirsupHQ

machine

Turn one line ("a turbofan jet engine", "a mechanical watch", "an LVAD heart pump") into a photoreal, physics based, interactive 3D simulation of that machine in a single HTML file, plus a…

627349Images & art

lingzhi227

Agent Research Skills

49
lingzhi227

experiment-design

Design experiment plans with progressive stages — initial implementation, baseline tuning, creative research, and ablation studies. Plan baselines, datasets, hyperparameter sweeps, and…

Pack46260kScience

Science skills, explained.

Also searched as: scientific agent skills, bioinformatics skill, ai scientist skills, deepmind science skills.

What are the best Claude skills for science?

Right now the top-ranked science skills on Alyn are Arize Evaluator (GitHub), Arize Experiment (GitHub), Caveman Manage (JuliusBrussee). Rankings combine GitHub stars, installs, freshness and depth, and update live.

Are there official DeepMind skills?

Yes. google-deepmind/science-skills is published by Google DeepMind for agentic scientific workflows.

Do science skills replace domain review?

No. They speed up analysis; results still need expert review.

How do I install a science skill?

Run npx skills add owner/repo in your project, or copy the folder with SKILL.md into ~/.claude/skills. Every skill on this page has a ready-to-copy command.

Built a science skill? Get it ranked.

Submit a skill