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Best Claude skills for science

Science skills give agents domain tools for biology, chemistry, genomics and physics: database lookups, analysis pipelines and lab workflows. K-Dense's scientific-agent-skills and Google DeepMind's science-skills are the largest collections.

216 science skills · ranked live · November 2026

The top 10. Ranked by the Alyn Score.

  1. GitHub

    Awesome Copilot

    #1
    GitHub

    Arize Evaluator

    Handles LLM-as-judge evaluation workflows on Arize including creating/updating evaluators, running evaluations on spans or experiments, managing tasks, trigger-run operations, column…

    Pack41k2.4MScore 85
    Details
  2. GitHub

    Awesome Copilot

    #2
    GitHub

    Arize Experiment

    Creates, runs, and analyzes Arize experiments for evaluating and comparing model performance. Covers experiment CRUD, exporting runs, comparing results, and evaluation workflows using the…

    Pack41k2.4MScore 85
    Details
  3. #3
    JuliusBrussee

    Caveman Manage

    Inspect Caveman Cloud's experiment lifecycle and block unsafe execution. Use when asked to start, approve, cancel, promote or roll back a Caveman experiment.

    Pack119k4.8MScore 85
    Details
  4. K-Dense

    Scientific Agent Skills

    #4
    K-Dense

    Alphagenome

    Looks up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq…

    Pack57k328kScore 84
    Details
  5. K-Dense

    Scientific Agent Skills

    #5
    K-Dense

    Analytical Method Validation

    Plans, executes, and documents validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP //, ICH M10 bioanalytical, CLSI EP, or…

    Pack57k328kScore 84
    Details
  6. K-Dense

    Scientific Agent Skills

    #6
    K-Dense

    Arbor

    Applies Arbor Hypothesis Tree Refinement to research artifacts with repeatable evaluators, including model training, agent harnesses, data synthesis and benchmark optimization. Uses…

    Pack57k328kScore 84
    Details
  7. #7
    Yuan1z0825

    Nature Paper Card

    Build a structured deep-reading Paper Card for one scientific paper, analysing methods, experiment-to-claim evidence, limitations, and research ideas. Use for 论文精读卡、方法拆解、证据链分析; not…

    Pack53k301kScore 84
    Details
  8. sickn33

    Agentic Awesome Skills

    #8
    sickn33

    Ab Testing

    When the user wants to plan, design, or implement an A/B test or experiment, or build a growth experimentation program.

    Pack49k584kScore 83
    Details
  9. #9
    Yuan1z0825

    Nature Social Science

    社会科学及相邻学科学术写作与选题论证工作台,覆盖选题构思、文献梳理、论证组织、学术表达四大要素。Use for 找论文题目/研究问题、把兴趣或宽泛主题变成可讨论的研究方向、文献综述与领域版图、区分"研究少"与真正未决的知识问题、设计证据路线与主张边界、新颖性审计与"审稿人2"式攻击、博士/论文可行性评估、导师沟通话术、或检查论文中的过度断…

    Pack53k301kScore 82
    Details
  10. #10
    Yuan1z0825

    Nature Writing

    Draft or restructure scientific manuscript arguments, sections, and initial-submission materials from author-provided evidence. Use for 论文写作、章节起草、论证重构、正文压缩、首次投稿材料. Use nature-polishing for…

    Pack53k301kScore 82
    Details

What makes a great science skill.

  • Pinned, real libraries and databases with usage examples.

  • Validation steps that catch silent errors in pipelines.

  • Clear licensing for data sources.

All 216 science skills.

79
Yuan1z0825

nature-experiment-log

标准化实验日志记录——直接上传或读取本地图片、语音和文字,产出带 YAML frontmatter 的 Markdown;可选集成飞书 CLI 与 Obsidian。

Pack53k301kScience

Google DeepMind

Science Skills

72
Google DeepMind

clinvar-database

Use when needing clinical significance, pathogenicity classifications (e.g., Pathogenic, Benign, VUS), clinical evidence rationales, or finding "hard positive" benchmark controls for human…

Pack3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

dbsnp-database

Use when you want to look up, map, and search for short genetic variants (SNPs, indels) in NCBI's dbSNP database. Resolves between rsIDs, genomic coordinates in VCF format, and HGVS…

Pack3.4k91kBackend

Google DeepMind

Science Skills

72
Google DeepMind

embl-ebi-ols

Query and search the EMBL-EBI Ontology Lookup Service (OLS) for biomedical ontology terms, definitions, and hierarchies across 250+ ontologies (e.g., GO, DOID, HP). Use when the user asks…

Pack3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

encode-ccres-database

Query the ENCODE Registry of cis-Regulatory Elements (cCREs) via the SCREEN GraphQL API, or make custom queries to the ENCODE Portal REST API for experiments and files (ChIP-seq peaks…

Pack3.4k91kBackend

Google DeepMind

Science Skills

72
Google DeepMind

ensembl-database

Query the Ensembl database to resolve gene, transcript, and protein IDs, fetch genomic or protein sequences, retrieve gene structures (exons), and get variant consequence and effect…

Pack3.4k91kScience

wanshuiyin

Auto Claude Code Research In Sleep

72
wanshuiyin

experiment-plan

Turn a refined research proposal or method idea into a detailed, claim-driven experiment roadmap. Use after `research-refine`, or when the user asks for a detailed experiment plan, ablation…

Pack19k42kResearch

Google DeepMind

Science Skills

72
Google DeepMind

gtex-database

Use when you want to retrieve quantitative RNA expression data and variant eQTL information from the GTEx (Genotype-Tissue Expression) Project across 54 non-diseased tissue sites.

Pack3.4k91kBackend

Google DeepMind

Science Skills

72
Google DeepMind

human-protein-atlas-database

Use when you want to retrieve semi-quantitative protein expression and spatial localisation data from the Human Protein Atlas (HPA).

Pack3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

interpro-database

Identify domains, families, and sites in proteins; find all proteins in a family or sharing a domain; explore species distribution for a domain; annotate genomes with protein families and…

Pack3.4k91kBackend

Google DeepMind

Science Skills

72
Google DeepMind

literature-search-biorxiv

Browse and filter life sciences, biology, and medical preprints from bioRxiv and medRxiv. Supports fetching paper metadata by DOI, and browsing by date range with category and keyword…

Pack3.4k91kResearch

Google DeepMind

Science Skills

72
Google DeepMind

literature-search-europepmc

Search Europe PMC for scientific literature and download open-access full texts and PDFs. Retrieve full-text XML/plain text by PMCID, get citation lists and bibliography.

Pack3.4k91kResearch

Google DeepMind

Science Skills

72
Google DeepMind

literature-search-openalex

Query the OpenAlex scholarly database for research papers, authors, institutions, topics, sources, publishers, funders, geo-locations, and keywords. Use when searching academic papers…

Pack3.4k91kResearch

Google DeepMind

Science Skills

72
Google DeepMind

ncbi-sequence-fetch

Retrieve protein and nucleotide sequences from NCBI databases using E-utilities. Supports direct accession lookup, CDS translation, gene+organism search, locus lookup, PubMed-linked…

Pack3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

openfda-database

Query, search, and download data from the openFDA API for drugs, devices, foods, tobacco, cosmetics, animal and veterinary products, substances, and transparency data. Use for FDA adverse…

Pack3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

opentargets-database

Query Open Targets Platform for target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs, for therapeutic target identification.

Pack3.4k91kBackend

Google DeepMind

Science Skills

72
Google DeepMind

pdb-database

Use when you want to search for or download experimentally-determined 3D structures for biomolecules (proteins, nucleic acids, bound ligands). Supports searching by sequence similarity…

Pack3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

predictingthepast

Ancient text restoration, attribution, dating, contextualization, and embedding via Aeneas (Latin) / Ithaca (Ancient Greek). Use when asked to "restore", "attribute", "date"…

Pack3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

protein-sequence-similarity-search

Searches for homologous protein sequences using MMseqs2 (fast, default) or BLAST (comprehensive, fallback). Trigger this whenever the user provides a protein sequence or FASTA file and asks…

Pack3.4k91kScience

NVIDIA

Skills

71
NVIDIA

diffdock-nim

Run DiffDock molecular docking via NVIDIA NIM to predict small-molecule binding poses against protein targets. Use for DiffDock, molecular docking, ligand docking, blind docking, SMILES or…

Pack3.9k429kScience

NVIDIA

Skills

71
NVIDIA

drug-discovery-pipeline

NOTE: molecule and target inputs and your NGC_API_KEY are transmitted to external NVIDIA-hosted API endpoints on every call. Use local NIM containers for confidential or proprietary data…

Pack3.9k429kDevOps

Google DeepMind

Science Skills

71
Google DeepMind

foldseek-structural-search

Performs 3D structural searches of proteins against various databases (PDB, AlphaFold, CATH, MGnify, etc.) using the Foldseek API. Use ONLY when the user provides a physical 3D coordinate…

Pack3.4k91kScience

Google DeepMind

Science Skills

71
Google DeepMind

protein-sequence-msa

Performs multiple sequence alignment of proteins with EBI Clustal Omega. Use when you need to align multiple sequences to assess similarity, domain conservation, or key residue…

Pack3.4k91kScience

Google DeepMind

Science Skills

71
Google DeepMind

pubchem-database

Query PubChem, search by name/CID/SMILES, retrieve properties, similarity/substructure searches, bioactivity, for cheminformatics. Use when a user asks about a specific chemical, drug, or…

Pack3.4k91kScience

Google DeepMind

Science Skills

70
Google DeepMind

alphafold-database-fetch-and-analyze

Retrieve and analyze AlphaFold predicted structures for a protein. Use when the user provides a specific UniProt Accession ID and wants structural confidence metrics (pLDDT), domain…

Pack3.4k91kScience

Google DeepMind

Science Skills

70
Google DeepMind

alphagenome-atlas-website-links

Constructs deep-links and URLs for the AlphaGenome Atlas website. Supports generating single-variant exploration links (1-based VCF-style coordinates), genomic locus views (1-based closed…

Pack3.4k91kScience

Google DeepMind

Science Skills

70
Google DeepMind

alphagenome-variant-impact-score

Score, annotate, and analyze the functional impact of genetic variants using AlphaGenome Variant Impact (AVI) scores. Query variants in chr:pos:ref>alt format, annotate VCF/tabular…

Pack3.4k91kScience

Google DeepMind

Science Skills

70
Google DeepMind

jaspar-database

Query the JASPAR database for Transcription Factor (TF) binding profiles. Use when retrieving Position Frequency Matrices (PFMs) or Position Weight Matrices (PWMs) for specific TFs…

Pack3.4k91kScience

Google DeepMind

Science Skills

70
Google DeepMind

literature-search-arxiv

Search for scientific papers, preprints, and publications on arXiv. Extract metadata, abstracts, and download full-text PDFs or HTML versions of papers. Use when the user asks to find…

Pack3.4k91kResearch

wanshuiyin

Auto Claude Code Research In Sleep

68
wanshuiyin

analyze-results

Analyze ML experiment results, compute statistics, generate comparison tables and insights. Use when user says "analyze results", "compare", or needs to interpret experimental data.

Pack19k42kResearch

Google DeepMind

Science Skills

68
Google DeepMind

gnomad-database

Query the Genome Aggregation Database (gnomAD). Use when determining the rarity or allele frequency of specific genetic variants, retrieving gene constraint metrics (pLI, LOEUF) to assess…

Pack3.4k91kBackend

Google DeepMind

Science Skills

66
Google DeepMind

credentials

Instructions for handling API keys and credentials safely, verifying their presence, and prompting the user to add them if missing using a safe protocol.

Pack3.4k91kScience
64
brycewang-stanford

literature-review

Conduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv, bioRxiv, Semantic Scholar, etc.). This skill should be used when conducting systematic…

Pack5k2kResearch
64
brycewang-stanford

research-grants

Write competitive research proposals for NSF, NIH, DOE, DARPA, and Taiwan NSTC. Agency-specific formatting, review criteria, budget preparation, broader impacts, significance statements…

Pack5k2kResearch
64
brycewang-stanford

research-proposal

Generate academic research proposals for PhD applications. Use when user asks to "write a research proposal", "create PhD proposal", "generate research plan", "撰写研究计划", "写博士申请", "doctoral…

Pack5k2kResearch
64
brycewang-stanford

scientific-writing

Core skill for the deep research and writing tool. Write scientific manuscripts in full paragraphs (never bullet points). Use two-stage process with (1) section outlines with key points…

Pack5k2kScience

Science skills, explained.

Also searched as: scientific agent skills, bioinformatics skill, ai scientist skills, deepmind science skills.

What are the best Claude skills for science?

Right now the top-ranked science skills on Alyn are Arize Evaluator (GitHub), Arize Experiment (GitHub), Caveman Manage (JuliusBrussee). Rankings combine GitHub stars, installs, freshness and depth, and update live.

Are there official DeepMind skills?

Yes. google-deepmind/science-skills is published by Google DeepMind for agentic scientific workflows.

Do science skills replace domain review?

No. They speed up analysis; results still need expert review.

How do I install a science skill?

Run npx skills add owner/repo in your project, or copy the folder with SKILL.md into ~/.claude/skills. Every skill on this page has a ready-to-copy command.

Built a science skill? Get it ranked.

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