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Best Claude skills for science

Science skills give agents domain tools for biology, chemistry, genomics and physics: database lookups, analysis pipelines and lab workflows. K-Dense's scientific-agent-skills and Google DeepMind's science-skills are the largest collections.

216 science skills · ranked live · November 2026

The top 10. Ranked by the Alyn Score.

  1. GitHub

    Awesome Copilot

    #1
    GitHub

    Arize Evaluator

    Handles LLM-as-judge evaluation workflows on Arize including creating/updating evaluators, running evaluations on spans or experiments, managing tasks, trigger-run operations, column…

    Pack41k2.4MScore 85
    Details
  2. GitHub

    Awesome Copilot

    #2
    GitHub

    Arize Experiment

    Creates, runs, and analyzes Arize experiments for evaluating and comparing model performance. Covers experiment CRUD, exporting runs, comparing results, and evaluation workflows using the…

    Pack41k2.4MScore 85
    Details
  3. #3
    JuliusBrussee

    Caveman Manage

    Inspect Caveman Cloud's experiment lifecycle and block unsafe execution. Use when asked to start, approve, cancel, promote or roll back a Caveman experiment.

    Pack119k4.8MScore 85
    Details
  4. K-Dense

    Scientific Agent Skills

    #4
    K-Dense

    Alphagenome

    Looks up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq…

    Pack57k328kScore 84
    Details
  5. K-Dense

    Scientific Agent Skills

    #5
    K-Dense

    Analytical Method Validation

    Plans, executes, and documents validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP //, ICH M10 bioanalytical, CLSI EP, or…

    Pack57k328kScore 84
    Details
  6. K-Dense

    Scientific Agent Skills

    #6
    K-Dense

    Arbor

    Applies Arbor Hypothesis Tree Refinement to research artifacts with repeatable evaluators, including model training, agent harnesses, data synthesis and benchmark optimization. Uses…

    Pack57k328kScore 84
    Details
  7. #7
    Yuan1z0825

    Nature Paper Card

    Build a structured deep-reading Paper Card for one scientific paper, analysing methods, experiment-to-claim evidence, limitations, and research ideas. Use for 论文精读卡、方法拆解、证据链分析; not…

    Pack53k301kScore 84
    Details
  8. sickn33

    Agentic Awesome Skills

    #8
    sickn33

    Ab Testing

    When the user wants to plan, design, or implement an A/B test or experiment, or build a growth experimentation program.

    Pack49k584kScore 83
    Details
  9. #9
    Yuan1z0825

    Nature Social Science

    社会科学及相邻学科学术写作与选题论证工作台,覆盖选题构思、文献梳理、论证组织、学术表达四大要素。Use for 找论文题目/研究问题、把兴趣或宽泛主题变成可讨论的研究方向、文献综述与领域版图、区分"研究少"与真正未决的知识问题、设计证据路线与主张边界、新颖性审计与"审稿人2"式攻击、博士/论文可行性评估、导师沟通话术、或检查论文中的过度断…

    Pack53k301kScore 82
    Details
  10. #10
    Yuan1z0825

    Nature Writing

    Draft or restructure scientific manuscript arguments, sections, and initial-submission materials from author-provided evidence. Use for 论文写作、章节起草、论证重构、正文压缩、首次投稿材料. Use nature-polishing for…

    Pack53k301kScore 82
    Details

What makes a great science skill.

  • Pinned, real libraries and databases with usage examples.

  • Validation steps that catch silent errors in pipelines.

  • Clear licensing for data sources.

All 216 science skills.

62
foryourhealth111-pixel

biopython

Primary retained Python toolkit for molecular biology sequence work. Preferred for sequence manipulation, FASTA/FASTQ/GenBank parsing, Bio.Entrez, BLAST workflows, alignments, structures…

Pack3.8k950Science
62
brycewang-stanford

citation-management

Comprehensive citation management for academic research. Search Google Scholar and PubMed for papers, extract accurate metadata, validate citations, and generate properly formatted BibTeX…

Pack5k2kResearch
62
brycewang-stanford

peer-review

Systematic peer review toolkit. Evaluate methodology, statistics, design, reproducibility, ethics, figure integrity, reporting standards, for manuscript and grant review across disciplines.

Pack5k2kScience
62
brycewang-stanford

scholar-evaluation

Apply the ScholarEval framework to systematically evaluate scholarly work across quality dimensions (novelty, rigor, significance, and clarity). Use to critique academic papers, research…

Pack5k2kResearch
62
brycewang-stanford

scientific-critical-thinking

Evaluate research rigor. Assess methodology, experimental design, statistical validity, biases, confounding, evidence quality (GRADE, Cochrane ROB), for critical analysis of scientific…

Pack5k2kScience

GarethManning

Education Agent Skills

61
GarethManning

cognitive-tutoring-architecture-designer

Map knowledge components and skill hierarchies for a cognitive tutoring system or adaptive learning platform. Use when designing intelligent tutoring software or skill-based mastery systems.

Pack97225kEducation

GarethManning

Education Agent Skills

61
GarethManning

digital-worked-example-sequence

Create an interactive digital worked example sequence with fading for online or blended delivery. Use when building e-learning modules, LMS content, or app-based instruction.

Pack97225kEducation

GarethManning

Education Agent Skills

61
GarethManning

erroneous-example-designer

Design deliberately flawed examples that develop error-detection skills and deepen understanding. Use when students make characteristic errors and need practice spotting mistakes.

Pack97225kEducation

GarethManning

Education Agent Skills

61
GarethManning

formative-assessment-loop-designer

Design an adaptive assessment loop where each student response triggers the next instructional move. Use when building technology-enhanced formative assessment cycles.

Pack97225kEducation

GarethManning

Education Agent Skills

61
GarethManning

individual-spacing-algorithm-explainer

Explain and configure individual spacing algorithms using student performance data and forgetting curves. Use when personalising retention schedules in adaptive learning platforms.

Pack97225kEducation

GarethManning

Education Agent Skills

61
GarethManning

intelligent-tutoring-dialogue-designer

Script a multi-turn tutoring dialogue with branching responses for anticipated student difficulties. Use when designing AI tutors, chatbot interactions, or structured one-to-one support…

Pack97225kEducation

GarethManning

Education Agent Skills

61
GarethManning

learning-analytics-interpretation-guide

Interpret learning analytics data and translate dashboard findings into actionable teaching decisions. Use when reviewing LMS data, quiz patterns, or engagement metrics.

Pack97225kEducation

GarethManning

Education Agent Skills

61
GarethManning

metacognitive-monitoring-ai-contexts

Design metacognitive checkpoints that prevent AI-assisted learning from bypassing genuine understanding. Use when students use AI tools and may overestimate their own comprehension.

Pack97225kEducation

GarethManning

Education Agent Skills

61
GarethManning

productive-failure-desirable-difficulty-designer

Redesign a direct instruction sequence to include productive struggle before the explanation phase. Use when teaching concepts that benefit from failure-first approaches.

Pack97225kEducation

GarethManning

Education Agent Skills

61
GarethManning

self-explanation-prompt-designer

Create self-explanation prompts that deepen understanding of worked examples, texts, or diagrams. Use when students read material passively without engaging with underlying principles.

Pack97225kEducation

GarethManning

Education Agent Skills

61
GarethManning

worked-example-to-problem-solving-transition-designer

Design the transition from worked examples to independent problem-solving using expertise-reversal principles. Use when students follow examples but cannot solve problems alone.

Pack97225kEducation
59
foryourhealth111-pixel

adaptyv

Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing…

Pack3.8k950Science
58
foryourhealth111-pixel

bio-database-evidence

Unified biological database evidence owner. Use for gene annotation, variant clinical significance, cancer mutation evidence, GWAS trait associations, pathway mapping, target-disease…

Pack3.8k950Backend
58
jaechang-hits

scikit-survival-analysis

Time-to-event modeling with scikit-survival: Cox PH (elastic net), Random Survival Forests, Boosting, SVMs for censored data. C-index, Brier, time-dependent AUC; Kaplan-Meier, Nelson-Aalen…

Pack38713kScience
58
jaechang-hits

statistical-analysis

Guided statistical analysis: test choice, assumption checks, effect sizes, power, APA reporting. Pick tests, verify assumptions, or format results for publication. Covers frequentist…

Pack38713kData analysis
56
jaechang-hits

arboreto-grn-inference

GRN inference from expression via GRNBoost2 (gradient boosting) or GENIE3 (Random Forest). Load matrix, filter by TFs, infer TF-target-importance links, save network. Dask-parallelized to…

Pack38713kScience
56
jaechang-hits

biopython-molecular-biology

Molecular biology toolkit: sequence manipulation, FASTA/GenBank/PDB I/O, NCBI Entrez, BLAST automation, pairwise/MSA alignment, Bio.PDB, phylogenetic trees. Use for batch processing, custom…

Pack38713kScience
56
jaechang-hits

biopython-sequence-analysis

Biopython sequence analysis: parse FASTA/FASTQ/GenBank/GFF (SeqIO), NCBI Entrez (esearch/efetch/elink), remote/local BLAST, pairwise/MSA alignment (PairwiseAligner, MUSCLE/ClustalW)…

Pack38713kScience
56
jaechang-hits

cellpose-cell-segmentation

DL cell/nucleus segmentation for fluorescence and brightfield microscopy. Pre-trained models (cyto3, nuclei, tissuenet) and a generalist flow-based algorithm segment cells without…

Pack38713kScience
56
jaechang-hits

etetoolkit

ETE Toolkit (ETE3): Python phylogenetic tree analysis and visualization. Parse Newick/NHX/PhyloXML, traverse/annotate nodes, render figures with TreeStyle/NodeStyle, integrate NCBI…

Pack38713kScience
56
jaechang-hits

flowio-flow-cytometry

Parse/write FCS (Flow Cytometry) files v2.0-3.1. Events as NumPy, channel metadata, multi-dataset files, CSV/FCS export. Use FlowKit for gating/compensation.

Pack38713kScience
56
jaechang-hits

homer-motif-analysis

De novo and known TF motif enrichment in ChIP-seq/ATAC-seq peaks via HOMER. findMotifsGenome.pl finds over-represented patterns vs background; annotatePeaks.pl assigns context (TSS…

Pack38713kScience
56
jaechang-hits

macs3-peak-calling

Poisson-model peak caller for ChIP-seq/ATAC-seq BAMs. MACS3 callpeak finds enriched regions (TF sites or histone marks) vs input/IgG; outputs BED narrowPeak/broadPeak for motif analysis…

Pack38713kScience

zLanqing

Codex Claude Academic Skills

56
zLanqing

matplotlib

Low-level plotting library for full customization. Use when you need fine-grained control over every plot element, creating novel plot types, or integrating with specific scientific…

Pack5.9k3.2kScience
56
jaechang-hits

matplotlib-scientific-plotting

Low-level Python plotting for scientific figures: publication-quality line, scatter, bar, heatmap, contour, 3D; multi-panel layouts; fine control of every element. PNG/PDF/SVG export. Use…

Pack38713kScience
56
jaechang-hits

multipanel

Assemble multiple plots into ONE publication-ready multi-panel journal figure (e.g. Figure 1 with panels A, B, C). Use whenever the user asks to combine, compose, or lay out several plots…

Pack38713kData analysis
56
jaechang-hits

napari-image-viewer

Interactive viewer for microscopy. Displays 2D/3D/4D arrays as Image, Labels, Points, Shapes, Tracks layers; supports annotation, plugin analysis, headless screenshots. Core visualization…

Pack38713kImages & art
56
jaechang-hits

omics-plotting

omics-plotting: publication-style figure authoring for omics / bioinformatics results with matplotlib / seaborn. Read this before writing any plotting or figure code in any omics analysis —…

Pack38713kScience
56
jaechang-hits

opencv-bioimage-analysis

Computer vision for bio-image preprocessing, feature detection, real-time microscopy. Color conversion, morphology, contour/blob detection, template matching, optical flow on…

Pack38713kScience
56
jaechang-hits

opentrons-integration

Opentrons Protocol API v2 for OT-2/Flex: Python protocols for pipetting, serial dilutions, PCR, plate replication; control thermocycler, heater-shaker, magnetic, temperature modules. Use…

Pack38713kAutomation
56
jaechang-hits

plotly-interactive-plots

Interactive scientific visualization with Plotly. Two APIs: plotly.express (px) for one-liner DataFrame plots, plotly.graph_objects (go) for trace-level control. 40+ chart types with hover…

Pack38713kData analysis

Science skills, explained.

Also searched as: scientific agent skills, bioinformatics skill, ai scientist skills, deepmind science skills.

What are the best Claude skills for science?

Right now the top-ranked science skills on Alyn are Arize Evaluator (GitHub), Arize Experiment (GitHub), Caveman Manage (JuliusBrussee). Rankings combine GitHub stars, installs, freshness and depth, and update live.

Are there official DeepMind skills?

Yes. google-deepmind/science-skills is published by Google DeepMind for agentic scientific workflows.

Do science skills replace domain review?

No. They speed up analysis; results still need expert review.

How do I install a science skill?

Run npx skills add owner/repo in your project, or copy the folder with SKILL.md into ~/.claude/skills. Every skill on this page has a ready-to-copy command.

Built a science skill? Get it ranked.

Submit a skill