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Best Claude skills for science

Science skills give agents domain tools for biology, chemistry, genomics and physics: database lookups, analysis pipelines and lab workflows. K-Dense's scientific-agent-skills and Google DeepMind's science-skills are the largest collections.

216 science skills · ranked live · November 2026

The top 10. Ranked by the Alyn Score.

  1. GitHub

    Awesome Copilot

    #1
    GitHub

    Arize Evaluator

    Handles LLM-as-judge evaluation workflows on Arize including creating/updating evaluators, running evaluations on spans or experiments, managing tasks, trigger-run operations, column…

    Pack41k2.4MScore 85
    Details
  2. GitHub

    Awesome Copilot

    #2
    GitHub

    Arize Experiment

    Creates, runs, and analyzes Arize experiments for evaluating and comparing model performance. Covers experiment CRUD, exporting runs, comparing results, and evaluation workflows using the…

    Pack41k2.4MScore 85
    Details
  3. #3
    JuliusBrussee

    Caveman Manage

    Inspect Caveman Cloud's experiment lifecycle and block unsafe execution. Use when asked to start, approve, cancel, promote or roll back a Caveman experiment.

    Pack119k4.8MScore 85
    Details
  4. K-Dense

    Scientific Agent Skills

    #4
    K-Dense

    Alphagenome

    Looks up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq…

    Pack57k328kScore 84
    Details
  5. K-Dense

    Scientific Agent Skills

    #5
    K-Dense

    Analytical Method Validation

    Plans, executes, and documents validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP //, ICH M10 bioanalytical, CLSI EP, or…

    Pack57k328kScore 84
    Details
  6. K-Dense

    Scientific Agent Skills

    #6
    K-Dense

    Arbor

    Applies Arbor Hypothesis Tree Refinement to research artifacts with repeatable evaluators, including model training, agent harnesses, data synthesis and benchmark optimization. Uses…

    Pack57k328kScore 84
    Details
  7. #7
    Yuan1z0825

    Nature Paper Card

    Build a structured deep-reading Paper Card for one scientific paper, analysing methods, experiment-to-claim evidence, limitations, and research ideas. Use for 论文精读卡、方法拆解、证据链分析; not…

    Pack53k301kScore 84
    Details
  8. sickn33

    Agentic Awesome Skills

    #8
    sickn33

    Ab Testing

    When the user wants to plan, design, or implement an A/B test or experiment, or build a growth experimentation program.

    Pack49k584kScore 83
    Details
  9. #9
    Yuan1z0825

    Nature Social Science

    社会科学及相邻学科学术写作与选题论证工作台,覆盖选题构思、文献梳理、论证组织、学术表达四大要素。Use for 找论文题目/研究问题、把兴趣或宽泛主题变成可讨论的研究方向、文献综述与领域版图、区分"研究少"与真正未决的知识问题、设计证据路线与主张边界、新颖性审计与"审稿人2"式攻击、博士/论文可行性评估、导师沟通话术、或检查论文中的过度断…

    Pack53k301kScore 82
    Details
  10. #10
    Yuan1z0825

    Nature Writing

    Draft or restructure scientific manuscript arguments, sections, and initial-submission materials from author-provided evidence. Use for 论文写作、章节起草、论证重构、正文压缩、首次投稿材料. Use nature-polishing for…

    Pack53k301kScore 82
    Details

What makes a great science skill.

  • Pinned, real libraries and databases with usage examples.

  • Validation steps that catch silent errors in pipelines.

  • Clear licensing for data sources.

All 216 science skills.

56
jaechang-hits

plotly-interactive-visualization

Interactive visualization with Plotly. 40+ chart types (scatter, line, heatmap, 3D, geographic) with hover, zoom, pan. Two APIs: Plotly Express (DataFrame) and Graph Objects (fine control)…

Pack38713kScience
56
jaechang-hits

pyimagej-fiji-bridge

Python bridge to ImageJ2/Fiji for macros, plugins (Bio-Formats, TrackMate, Analyze Particles), NumPy↔ImagePlus/ImgLib2 exchange, and ImageJ Ops. Automates Fiji headlessly from Python. Use…

Pack38713kScience

zLanqing

Codex Claude Academic Skills

56
zLanqing

pymatgen

Materials science toolkit. Crystal structures (CIF, POSCAR), phase diagrams, band structure, DOS, Materials Project integration, format conversion, for computational materials science.

Pack5.9k3.2kScience

zLanqing

Codex Claude Academic Skills

56
zLanqing

pymoo

Multi-objective optimization framework. NSGA-II, NSGA-III, MOEA/D, Pareto fronts, constraint handling, benchmarks (ZDT, DTLZ), for engineering design and optimization problems.

Pack5.9k3.2kScience

zLanqing

Codex Claude Academic Skills

56
zLanqing

scientific-visualization

Meta-skill for publication-ready figures. Use when creating journal submission figures requiring multi-panel layouts, significance annotations, error bars, colorblind-safe palettes, and…

Pack5.9k3.2kScience
56
jaechang-hits

scientific-visualization

Guide for choosing and creating scientific visualizations for publications and talks. Covers chart-type selection by data structure, color theory for accessibility/print, figure…

Pack38713kScience
56
jaechang-hits

scikit-image-processing

Python image processing for microscopy and bioimage analysis. Read/write images, filter (Gaussian, median, LoG), segment (thresholding, watershed, active contours), measure region…

Pack38713kImages & art

zLanqing

Codex Claude Academic Skills

56
zLanqing

scikit-learn

Machine learning in Python with scikit-learn. Use when working with supervised learning (classification, regression), unsupervised learning (clustering, dimensionality reduction), model…

Pack5.9k3.2kScience
56
jaechang-hits

seaborn-statistical-plots

Statistical visualization on matplotlib with native pandas support. Auto aggregation, CIs, grouping for distributions (histplot, kdeplot), categorical (boxplot, violinplot), relational…

Pack38713kData analysis
56
jaechang-hits

seaborn-statistical-visualization

Statistical visualization on matplotlib + pandas. Distributions (histplot, kdeplot, violin, box), relational (scatter, line), categorical, regression, correlation heatmaps. Auto…

Pack38713kData analysis

zLanqing

Codex Claude Academic Skills

56
zLanqing

simpy

Process-based discrete-event simulation framework in Python. Use this skill when building simulations of systems with processes, queues, resources, and time-based events such as…

Pack5.9k3.2kScience
56
jaechang-hits

single-cell-annotation

Best practices for single-cell RNA-seq cell type annotation including marker-based, reference-based, and automated classification approaches.

Pack38713kScience

zLanqing

Codex Claude Academic Skills

56
zLanqing

statistical-analysis

Guided statistical analysis with test selection and reporting. Use when you need help choosing appropriate tests for your data, assumption checking, power analysis, and APA-formatted…

Pack5.9k3.2kData analysis
56
jaechang-hits

statistical-significance-annotation

Guide for annotating statistical significance (p-value asterisks) on comparison plots. Covers standard notation (ns, *, **, ***, ****), matplotlib bracket+asterisk implementation, and use…

Pack38713kData analysis

zLanqing

Codex Claude Academic Skills

56
zLanqing

timesfm-forecasting

Zero-shot time series forecasting with Google's TimesFM foundation model. Use for any univariate time series (sales, sensors, energy, vitals, weather) without training a custom model…

Pack5.9k3.2kScience
56
jaechang-hits

trackpy-particle-tracking

Python library for single-particle tracking (SPT) in video microscopy via the Crocker-Grier algorithm. Locate particles (fluorescent spots, colloids, vesicles, cells) per frame, link into…

Pack38713kScience
55
GPTomics

bio-single-cell-splicing

Analyzes alternative splicing at single-cell resolution. The first decision is library chemistry — 10X 3' is fundamentally limited (RT primes from poly-A, R2 falls in 3' UTR, <0.1 junction…

Pack1.2k1.3kScience
55
GPTomics

bio-splice-variant-prediction

Predicts whether a DNA variant alters mRNA splicing using sequence-based deep-learning tools — SpliceAI (10kb context dilated CNN, clinical default), Pangolin (multi-tissue), MMSplice…

Pack1.2k1.3kScience
55
GPTomics

bio-splicing-qc

Assesses RNA-seq data quality specifically for alternative splicing analysis. QC layers include experimental design audit (library prep, read length, depth, replicates), STAR 2-pass…

Pack1.2k1.3kScience

zLanqing

Codex Claude Academic Skills

54
zLanqing

astropy

Comprehensive Python library for astronomy and astrophysics. This skill should be used when working with astronomical data including celestial coordinates, physical units, FITS files…

Pack5.9k3.2kScience

zLanqing

Codex Claude Academic Skills

54
zLanqing

matlab

MATLAB and GNU Octave numerical computing for matrix operations, data analysis, visualization, and scientific computing. Use when writing MATLAB/Octave scripts for linear algebra, signal…

Pack5.9k3.2kScience

zLanqing

Codex Claude Academic Skills

54
zLanqing

networkx

Comprehensive toolkit for creating, analyzing, and visualizing complex networks and graphs in Python. Use when working with network/graph data structures, analyzing relationships between…

Pack5.9k3.2kScience

zLanqing

Codex Claude Academic Skills

54
zLanqing

paper-lookup

Search 10 academic paper databases via REST APIs for research papers, preprints, and scholarly articles. Covers PubMed, PMC (full text), bioRxiv, medRxiv, arXiv, OpenAlex, Crossref…

Pack5.9k3.2kResearch

zLanqing

Codex Claude Academic Skills

54
zLanqing

pdf

Use this skill whenever the user wants to do anything with PDF files. This includes reading or extracting text/tables from PDFs, combining or merging multiple PDFs into one, splitting PDFs…

Pack5.9k3.2kDocuments

zLanqing

Codex Claude Academic Skills

54
zLanqing

qutip

Quantum physics simulation library for open quantum systems. Use when studying master equations, Lindblad dynamics, decoherence, quantum optics, or cavity QED. Best for physics research…

Pack5.9k3.2kScience

zLanqing

Codex Claude Academic Skills

54
zLanqing

scientific-toolkit-skill

Research computing toolkit for optoelectronic information science and engineering, MATLAB/Octave, Python scientific analysis, signal processing, image processing, statistics, simulation…

Pack5.9k3.2kScience

zLanqing

Codex Claude Academic Skills

54
zLanqing

seaborn

Statistical visualization with pandas integration. Use for quick exploration of distributions, relationships, and categorical comparisons with attractive defaults. Best for box plots…

Pack5.9k3.2kScience

zLanqing

Codex Claude Academic Skills

54
zLanqing

statsmodels

Statistical models library for Python. Use when you need specific model classes (OLS, GLM, mixed models, ARIMA) with detailed diagnostics, residuals, and inference. Best for econometrics…

Pack5.9k3.2kScience

zLanqing

Codex Claude Academic Skills

54
zLanqing

sympy

Use this skill when working with symbolic mathematics in Python. This skill should be used for symbolic computation tasks including solving equations algebraically, performing calculus…

Pack5.9k3.2kScience

zLanqing

Codex Claude Academic Skills

54
zLanqing

xlsx

Use this skill any time a spreadsheet file is the primary input or output. This means any task where the user wants to: open, read, edit, or fix an existing .xlsx, .xlsm, .csv, or .tsv file…

Pack5.9k3.2kDocuments
53
GPTomics

bio-isoform-switching

Analyzes differential transcript usage (DTU) and isoform switches with functional consequence prediction (NMD via 50nt rule, ORF disruption, protein domain loss/gain, signal peptide…

Pack1.2k1.3kScience
49
GPTomics

clawhub-installer

Installs 425 bioinformatics skills covering sequence analysis, RNA-seq, single-cell, variant calling, metagenomics, structural biology, and 56 more categories. Use when setting up…

Pack1.2k1.3kScience

staruhub

ClaudeSkills

48
staruhub

podcast-generator

用火山引擎 Podcast AI 模型生成中文双人对话播客。当用户要把文章、报告、话题文本转成播客音频、生成对话式音频内容时使用,需要环境具备火山引擎 APP_ID 和 ACCESS_KEY。支持 mp3/ogg_opus/pcm/aac、语速调节、自定义音色、断点续传。不用于:单人朗读式 TTS(用普通语音合成)、英文播客(模型主要优化中文)、播客文稿本身的撰写(先用写作类…

Pack7361.4kScience

staruhub

ClaudeSkills

48
staruhub

university-exam-prep

大学备考苏格拉底式学习助手,专为应对"面向课本和PPT考试"设计。当用户说"帮我复习"、"准备考试"、"备考"、"期末复习"、"模拟学习"、"突击复习"等时触发。核心特点:(1)强制要求用户上传课本/PPT/考纲等原始材料——没有材料就无法有效辅导;(2)使用苏格拉底式提问法,不直接灌输而是引导思考;(3)专注于应用型和理解型内容,而非纯…

Pack7361.4kScience

staruhub

ClaudeSkills

47
staruhub

weather-forecast-report

将天气要素(风速、能见度、降雨量等)单站预报系统的项目文档、模型、报告、评估结果整理成符合省级自然科学基金项目编写规范的专题研究报告。适用于:(1) 基于Claude Code + OpenSpec开发的气象预报系统结题报告编写,(2) 将技术文档转换为学术研究报告格式,(3) 生成符合省级自然科学基金规范的专题研究报告,(4) 整合项目…

Pack7361.4kScience

lingzhi227

Agent Research Skills

46
lingzhi227

code-debugging

Debug experiment code with structured error analysis. Categorize errors, apply targeted fixes with retry logic, and use reflection to prevent recurring issues. Use when experiment code…

Pack46260kCoding

Science skills, explained.

Also searched as: scientific agent skills, bioinformatics skill, ai scientist skills, deepmind science skills.

What are the best Claude skills for science?

Right now the top-ranked science skills on Alyn are Arize Evaluator (GitHub), Arize Experiment (GitHub), Caveman Manage (JuliusBrussee). Rankings combine GitHub stars, installs, freshness and depth, and update live.

Are there official DeepMind skills?

Yes. google-deepmind/science-skills is published by Google DeepMind for agentic scientific workflows.

Do science skills replace domain review?

No. They speed up analysis; results still need expert review.

How do I install a science skill?

Run npx skills add owner/repo in your project, or copy the folder with SKILL.md into ~/.claude/skills. Every skill on this page has a ready-to-copy command.

Built a science skill? Get it ranked.

Submit a skill