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Best Claude skills for science

Science skills give agents domain tools for biology, chemistry, genomics and physics: database lookups, analysis pipelines and lab workflows. K-Dense's scientific-agent-skills and Google DeepMind's science-skills are the largest collections.

117 science skills · ranked live · November 2026

The top 10. Ranked by the Alyn Score.

  1. GitHub

    Awesome Copilot

    #1
    GitHub

    Arize Evaluator

    Handles LLM-as-judge evaluation workflows on Arize including creating/updating evaluators, running evaluations on spans or experiments, managing tasks, trigger-run operations, column…

    41k2.4MScore 85
    Details
  2. GitHub

    Awesome Copilot

    #2
    GitHub

    Arize Experiment

    Creates, runs, and analyzes Arize experiments for evaluating and comparing model performance. Covers experiment CRUD, exporting runs, comparing results, and evaluation workflows using the…

    41k2.4MScore 85
    Details
  3. #3
    JuliusBrussee

    Caveman Manage

    Inspect Caveman Cloud's experiment lifecycle and block unsafe execution. Use when asked to start, approve, cancel, promote or roll back a Caveman experiment.

    119k4.8MScore 85
    Details
  4. K-Dense

    Scientific Agent Skills

    #4
    K-Dense

    Alphagenome

    Looks up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq…

    57k328kScore 84
    Details
  5. K-Dense

    Scientific Agent Skills

    #5
    K-Dense

    Analytical Method Validation

    Plans, executes, and documents validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP //, ICH M10 bioanalytical, CLSI EP, or…

    57k328kScore 84
    Details
  6. K-Dense

    Scientific Agent Skills

    #6
    K-Dense

    Arbor

    Applies Arbor Hypothesis Tree Refinement to research artifacts with repeatable evaluators, including model training, agent harnesses, data synthesis and benchmark optimization. Uses…

    57k328kScore 84
    Details
  7. sickn33

    Agentic Awesome Skills

    #7
    sickn33

    Ab Testing

    When the user wants to plan, design, or implement an A/B test or experiment, or build a growth experimentation program.

    49k584kScore 83
    Details
  8. GitHub

    Awesome Copilot

    #8
    GitHub

    Autoresearch

    Autonomous iterative experimentation loop for any programming task. Guides the user through defining goals, measurable metrics, and scope constraints, then runs an autonomous loop of code…

    41k2.4MScore 83
    Details
  9. #9
    davila7

    Data Scientist

    Expert data scientist for advanced analytics, machine learning, and statistical modeling. Handles complex data analysis, predictive modeling, and business intelligence.

    33k285kScore 78
    Details
  10. Jeffallan

    Claude Skills

    #10
    Jeffallan

    Chaos Engineer

    Designs chaos experiments, creates failure injection frameworks, and facilitates game day exercises for distributed systems — producing runbooks, experiment manifests, rollback procedures…

    12k457kScore 77
    Details

What makes a great science skill.

  • Pinned, real libraries and databases with usage examples.

  • Validation steps that catch silent errors in pipelines.

  • Clear licensing for data sources.

All 117 science skills.

GitHub

Awesome Copilot

85
GitHub

arize-evaluator

Handles LLM-as-judge evaluation workflows on Arize including creating/updating evaluators, running evaluations on spans or experiments, managing tasks, trigger-run operations, column…

41k2.4MAI engineering

GitHub

Awesome Copilot

85
GitHub

arize-experiment

Creates, runs, and analyzes Arize experiments for evaluating and comparing model performance. Covers experiment CRUD, exporting runs, comparing results, and evaluation workflows using the…

41k2.4MScience
85
JuliusBrussee

caveman-manage

Inspect Caveman Cloud's experiment lifecycle and block unsafe execution. Use when asked to start, approve, cancel, promote or roll back a Caveman experiment.

119k4.8MCoding

K-Dense

Scientific Agent Skills

84
K-Dense

alphagenome

Looks up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq…

57k328kScience

K-Dense

Scientific Agent Skills

84
K-Dense

analytical-method-validation

Plans, executes, and documents validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP //, ICH M10 bioanalytical, CLSI EP, or…

57k328kScience

K-Dense

Scientific Agent Skills

84
K-Dense

arbor

Applies Arbor Hypothesis Tree Refinement to research artifacts with repeatable evaluators, including model training, agent harnesses, data synthesis and benchmark optimization. Uses…

57k328kScience

sickn33

Agentic Awesome Skills

83
sickn33

ab-testing

When the user wants to plan, design, or implement an A/B test or experiment, or build a growth experimentation program.

49k584kTesting

GitHub

Awesome Copilot

83
GitHub

autoresearch

Autonomous iterative experimentation loop for any programming task. Guides the user through defining goals, measurable metrics, and scope constraints, then runs an autonomous loop of code…

41k2.4MScience
78
davila7

data-scientist

Expert data scientist for advanced analytics, machine learning, and statistical modeling. Handles complex data analysis, predictive modeling, and business intelligence.

33k285kScience

Jeffallan

Claude Skills

77
Jeffallan

chaos-engineer

Designs chaos experiments, creates failure injection frameworks, and facilitates game day exercises for distributed systems — producing runbooks, experiment manifests, rollback procedures…

12k457kCoding
77
gamedev-skills

godot-physics

Use Godot 4.7 physics bodies and detection in 2D and 3D: RigidBody, StaticBody, Area, and CharacterBody; collision layers vs masks; contact/overlap signals; and raycasts (RayCast nodes and…

8.2k748kGame development
77
gamedev-skills

physics-tuning

Tune game physics for stable, good-feeling motion — fixed vs variable timestep, render interpolation, mass/gravity/drag, continuous collision detection (CCD) to stop tunneling, fixing…

8.2k748kScience

Jeffallan

Claude Skills

76
Jeffallan

game-developer

Use when building game systems, implementing Unity/Unreal Engine features, or optimizing game performance. Invoke to implement ECS architecture, configure physics systems and colliders, set…

12k457kGame development

Expo

Skills

75
Expo

expo-migrate-module

Migrate an existing Apple/Swift Expo native module from the Expo Modules API 1.0 definition DSL to the 2.0 macro API (sometimes called v2) while preserving its JavaScript and TypeScript…

4.1k1.1MMobile

wanshuiyin

Auto Claude Code Research In Sleep

74
wanshuiyin

experiment-queue

SSH job queue for multi-seed/multi-config ML experiments with OOM-aware retry, stale-screen cleanup, and wave-transition race prevention. Use when user says "batch experiments", "队列实验"…

19k42kScience

Google DeepMind

Science Skills

72
Google DeepMind

alphagenome-single-variant-analysis

Analyzes genetic variant effects on gene expression (RNA-seq), chromatin accessibility (DNASE), histone marks (ChIP), and transcription factors using the AlphaGenome API. Use when the user…

3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

chembl-database

Query the ChEMBL database for bioactive molecules, drug targets, bioactivity data, approved drugs, and chemical structures. Use when the user asks about compounds, targets, IC50/Ki values…

3.4k91kBackend

Google DeepMind

Science Skills

72
Google DeepMind

clinical-trials-database

Query ClinicalTrials.gov via APIv2. Use when you want to search for trials by condition, drug, location, status, or phase; retrieve trial details by NCT ID; check eligibility/inclusion…

3.4k91kScience

wanshuiyin

Auto Claude Code Research In Sleep

72
wanshuiyin

experiment-audit

Audit experiment integrity before claiming results. Uses cross-model review (external reviewer backend) to check for fake ground truth, score normalization fraud, phantom results, and…

19k42kScience

wanshuiyin

Auto Claude Code Research In Sleep

72
wanshuiyin

experiment-bridge

Workflow 1.5: Bridge between idea discovery and auto review. Reads EXPERIMENT_PLAN.md, implements experiment code, deploys to GPU, collects initial results. Use when user says "实现实验"…

19k42kScience

alirezarezvani

Claude Skills

71
alirezarezvani

chaos-experiment

30k240kScience

Hugging Face

Skills

71
Hugging Face

huggingface-trackio

Track and visualize ML training experiments with Trackio. Use when logging metrics during training (Python API), firing alerts for training diagnostics, or retrieving/analyzing logged…

11k42kAI engineering

wondelai

Skills

71
wondelai

lean-ux

Apply lean thinking to UX: hypothesis-driven design, collaborative sketching, and rapid experiments instead of heavy deliverables. Use when the user mentions "Lean UX", "design hypothesis"…

2.7k335kDesign

GarethManning

Education Agent Skills

61
GarethManning

adaptive-hint-sequence-designer

Generate a cascading hint sequence for a problem type, revealing progressively without giving answers. Use when designing tutoring dialogues or scaffolded worksheets.

97125kEducation

GarethManning

Education Agent Skills

61
GarethManning

ai-facilitated-collaborative-learning-designer

Design AI-supported collaborative tasks that structure group interaction and address participation problems. Use when students struggle to collaborate effectively on group tasks.

97125kEducation

GarethManning

Education Agent Skills

61
GarethManning

ai-feedback-design-principles

Audit and redesign AI-generated feedback for pedagogical quality, timing, and learning impact. Use when building or reviewing automated feedback in digital learning tools.

97125kEducation

aipoch

Medical Research Skills

56
aipoch

slide-deck-for-lab-meeting

Structures research progress into focused and actionable slides for lab meetings or project reviews without inventing missing content.

2k898Research

growthenginenowoslawski

Coldoutboundskills

54
growthenginenowoslawski

experiment-design

Framework for running single-variable cold email experiments. Defines experiment types (list-only, copy-only, combined), confidence weighting, minimum sample sizes, and success criteria…

8092.3kScience
52
kwakseongjae

omd-experiment-gallery

N개 brand experiment를 한 화면에서 비교하는 gallery index.html을 생성. 각 카드는 brand name, wow rating, multi-turn refinement deltas, iframe scaled preview, standalone link 포함. '결과물 한 번에 보여줘', '갤러리 만들어'…

580653Design
52
kwakseongjae

omd-lab-02-design-harness

OmD Lab #02 — 디자인 하네스 정교화 실험. 동일 task를 v1, v2, v3... 버전별 하네스 설정으로 돌려서 산출물 품질·토큰 비용·iteration 수·persona ABANDON 율을 비교. 트리거 — '/omd-lab-02', '하네스 lab 시작', '디자인 하네스 v2 돌려서 비교', 'lab #02 자동 비교'.

580653Design

K-Dense

Scientific Agent Skills

84
K-Dense

arboreto

Infers candidate gene regulatory networks from bulk or single-cell expression data using AertsLab Arboreto GRNBoost2 and GENIE3. Use for transcription factor-target association ranking…

57k328kScience

K-Dense

Scientific Agent Skills

84
K-Dense

autoskill

Analyzes user-requested Screenpipe history windows to detect repeated research workflows, match existing scientific skills, and stage new skill drafts or composition recipes for review…

57k328kScience

K-Dense

Scientific Agent Skills

84
K-Dense

bids

Organizes, queries, validates, and converts Brain Imaging Data Structure (BIDS) datasets. Supports organizing neuroscience and biomedical data (MRI, EEG, MEG, iEEG, PET, microscopy, NIRS…

57k328kScience

K-Dense

Scientific Agent Skills

84
K-Dense

bioservices

Provides a Python interface to bioinformatics services including UniProt, KEGG, ChEMBL, Reactome, QuickGO, and UniChem. Used for cross-database protein annotation, pathway retrieval…

57k328kScience

K-Dense

Scientific Agent Skills

84
K-Dense

bulk-rnaseq

Prepares bulk RNA-seq FASTQ, Salmon, STAR or featureCounts output for gene-level differential expression. Covers nf-core/rnaseq and standalone quantification, biological replication…

57k328kScience

K-Dense

Scientific Agent Skills

84
K-Dense

cantera

Runs Cantera homogeneous chemical reactors and evaluates ignition delay with mechanism provenance, conservation checks, and numerical refinement. Use for combustion kinetics, closed…

57k328kScience

Science skills, explained.

Also searched as: scientific agent skills, bioinformatics skill, ai scientist skills, deepmind science skills.

What are the best Claude skills for science?

Right now the top-ranked science skills on Alyn are Arize Evaluator (GitHub), Arize Experiment (GitHub), Caveman Manage (JuliusBrussee). Rankings combine GitHub stars, installs, freshness and depth, and update live.

Are there official DeepMind skills?

Yes. google-deepmind/science-skills is published by Google DeepMind for agentic scientific workflows.

Do science skills replace domain review?

No. They speed up analysis; results still need expert review.

How do I install a science skill?

Run npx skills add owner/repo in your project, or copy the folder with SKILL.md into ~/.claude/skills. Every skill on this page has a ready-to-copy command.

Built a science skill? Get it ranked.

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