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Best Claude skills for science

Science skills give agents domain tools for biology, chemistry, genomics and physics: database lookups, analysis pipelines and lab workflows. K-Dense's scientific-agent-skills and Google DeepMind's science-skills are the largest collections.

117 science skills · ranked live · November 2026

The top 10. Ranked by the Alyn Score.

  1. GitHub

    Awesome Copilot

    #1
    GitHub

    Arize Evaluator

    Handles LLM-as-judge evaluation workflows on Arize including creating/updating evaluators, running evaluations on spans or experiments, managing tasks, trigger-run operations, column…

    41k2.4MScore 85
    Details
  2. GitHub

    Awesome Copilot

    #2
    GitHub

    Arize Experiment

    Creates, runs, and analyzes Arize experiments for evaluating and comparing model performance. Covers experiment CRUD, exporting runs, comparing results, and evaluation workflows using the…

    41k2.4MScore 85
    Details
  3. #3
    JuliusBrussee

    Caveman Manage

    Inspect Caveman Cloud's experiment lifecycle and block unsafe execution. Use when asked to start, approve, cancel, promote or roll back a Caveman experiment.

    119k4.8MScore 85
    Details
  4. K-Dense

    Scientific Agent Skills

    #4
    K-Dense

    Alphagenome

    Looks up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq…

    57k328kScore 84
    Details
  5. K-Dense

    Scientific Agent Skills

    #5
    K-Dense

    Analytical Method Validation

    Plans, executes, and documents validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP //, ICH M10 bioanalytical, CLSI EP, or…

    57k328kScore 84
    Details
  6. K-Dense

    Scientific Agent Skills

    #6
    K-Dense

    Arbor

    Applies Arbor Hypothesis Tree Refinement to research artifacts with repeatable evaluators, including model training, agent harnesses, data synthesis and benchmark optimization. Uses…

    57k328kScore 84
    Details
  7. sickn33

    Agentic Awesome Skills

    #7
    sickn33

    Ab Testing

    When the user wants to plan, design, or implement an A/B test or experiment, or build a growth experimentation program.

    49k584kScore 83
    Details
  8. GitHub

    Awesome Copilot

    #8
    GitHub

    Autoresearch

    Autonomous iterative experimentation loop for any programming task. Guides the user through defining goals, measurable metrics, and scope constraints, then runs an autonomous loop of code…

    41k2.4MScore 83
    Details
  9. #9
    davila7

    Data Scientist

    Expert data scientist for advanced analytics, machine learning, and statistical modeling. Handles complex data analysis, predictive modeling, and business intelligence.

    33k285kScore 78
    Details
  10. Jeffallan

    Claude Skills

    #10
    Jeffallan

    Chaos Engineer

    Designs chaos experiments, creates failure injection frameworks, and facilitates game day exercises for distributed systems — producing runbooks, experiment manifests, rollback procedures…

    12k457kScore 77
    Details

What makes a great science skill.

  • Pinned, real libraries and databases with usage examples.

  • Validation steps that catch silent errors in pipelines.

  • Clear licensing for data sources.

All 117 science skills.

wanshuiyin

Auto Claude Code Research In Sleep

72
wanshuiyin

experiment-plan

Turn a refined research proposal or method idea into a detailed, claim-driven experiment roadmap. Use after `research-refine`, or when the user asks for a detailed experiment plan, ablation…

19k42kResearch

Google DeepMind

Science Skills

72
Google DeepMind

gtex-database

Use when you want to retrieve quantitative RNA expression data and variant eQTL information from the GTEx (Genotype-Tissue Expression) Project across 54 non-diseased tissue sites.

3.4k91kBackend

Google DeepMind

Science Skills

72
Google DeepMind

human-protein-atlas-database

Use when you want to retrieve semi-quantitative protein expression and spatial localisation data from the Human Protein Atlas (HPA).

3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

interpro-database

Identify domains, families, and sites in proteins; find all proteins in a family or sharing a domain; explore species distribution for a domain; annotate genomes with protein families and…

3.4k91kBackend

Google DeepMind

Science Skills

72
Google DeepMind

literature-search-biorxiv

Browse and filter life sciences, biology, and medical preprints from bioRxiv and medRxiv. Supports fetching paper metadata by DOI, and browsing by date range with category and keyword…

3.4k91kResearch

Google DeepMind

Science Skills

72
Google DeepMind

literature-search-europepmc

Search Europe PMC for scientific literature and download open-access full texts and PDFs. Retrieve full-text XML/plain text by PMCID, get citation lists and bibliography.

3.4k91kResearch

Google DeepMind

Science Skills

72
Google DeepMind

literature-search-openalex

Query the OpenAlex scholarly database for research papers, authors, institutions, topics, sources, publishers, funders, geo-locations, and keywords. Use when searching academic papers…

3.4k91kResearch

Google DeepMind

Science Skills

72
Google DeepMind

ncbi-sequence-fetch

Retrieve protein and nucleotide sequences from NCBI databases using E-utilities. Supports direct accession lookup, CDS translation, gene+organism search, locus lookup, PubMed-linked…

3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

openfda-database

Query, search, and download data from the openFDA API for drugs, devices, foods, tobacco, cosmetics, animal and veterinary products, substances, and transparency data. Use for FDA adverse…

3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

opentargets-database

Query Open Targets Platform for target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs, for therapeutic target identification.

3.4k91kBackend

Google DeepMind

Science Skills

72
Google DeepMind

pdb-database

Use when you want to search for or download experimentally-determined 3D structures for biomolecules (proteins, nucleic acids, bound ligands). Supports searching by sequence similarity…

3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

predictingthepast

Ancient text restoration, attribution, dating, contextualization, and embedding via Aeneas (Latin) / Ithaca (Ancient Greek). Use when asked to "restore", "attribute", "date"…

3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

protein-sequence-similarity-search

Searches for homologous protein sequences using MMseqs2 (fast, default) or BLAST (comprehensive, fallback). Trigger this whenever the user provides a protein sequence or FASTA file and asks…

3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

pubmed-database

Search PubMed for scientific literature, including published clinical trials. Fetch abstracts and full text. Link published research to biological databases (gene, protein, nucleotide…

3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

reactome-database

Query the Reactome database (Analysis and Content Services). Use when the user asks about pathway analysis, gene list enrichment, retrieving results by token, finding unmapped or not-found…

3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

ucsc-conservation-and-tfbs

Fetch Evolutionary Conservation scores (phyloP, phastCons) and Transcription Factor Binding Sites (TFBS) from the UCSC Genome Browser. Use when analyzing whether genomic variants or regions…

3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

uniprot-database

Access protein metadata, function, taxonomy, and sequences across UniProtKB, UniParc, and UniRef. Use when searching for proteins, mapping identifiers, or retrieving functional annotations…

3.4k91kScience

Google DeepMind

Science Skills

72
Google DeepMind

workflow-skill-creator

Distills a completed user workflow or interaction into a reusable agent skill. Use when the user asks to turn their workflow, interaction, or multi-step process into a skill, or when they…

3.4k91kAutomation

Google DeepMind

Science Skills

71
Google DeepMind

foldseek-structural-search

Performs 3D structural searches of proteins against various databases (PDB, AlphaFold, CATH, MGnify, etc.) using the Foldseek API. Use ONLY when the user provides a physical 3D coordinate…

3.4k91kScience

Google DeepMind

Science Skills

71
Google DeepMind

protein-sequence-msa

Performs multiple sequence alignment of proteins with EBI Clustal Omega. Use when you need to align multiple sequences to assess similarity, domain conservation, or key residue…

3.4k91kScience

Google DeepMind

Science Skills

71
Google DeepMind

pubchem-database

Query PubChem, search by name/CID/SMILES, retrieve properties, similarity/substructure searches, bioactivity, for cheminformatics. Use when a user asks about a specific chemical, drug, or…

3.4k91kScience

Google DeepMind

Science Skills

71
Google DeepMind

quickgo-database

Query the QuickGO and Evidence & Conclusion Ontology (ECO) REST API. Use this when you need to map genes to biological processes, molecular functions, or cellular components, find genes…

3.4k91kBackend

Google DeepMind

Science Skills

71
Google DeepMind

unibind-database

Queries the UniBind database for experimentally validated transcription factor (TF) binding sites. Use when retrieving direct TF-DNA interaction datasets, downloading binding site…

3.4k91kBackend

Google DeepMind

Science Skills

70
Google DeepMind

alphafold-database-fetch-and-analyze

Retrieve and analyze AlphaFold predicted structures for a protein. Use when the user provides a specific UniProt Accession ID and wants structural confidence metrics (pLDDT), domain…

3.4k91kScience

Google DeepMind

Science Skills

70
Google DeepMind

alphagenome-atlas-website-links

Constructs deep-links and URLs for the AlphaGenome Atlas website. Supports generating single-variant exploration links (1-based VCF-style coordinates), genomic locus views (1-based closed…

3.4k91kScience

Google DeepMind

Science Skills

70
Google DeepMind

alphagenome-variant-impact-score

Score, annotate, and analyze the functional impact of genetic variants using AlphaGenome Variant Impact (AVI) scores. Query variants in chr:pos:ref>alt format, annotate VCF/tabular…

3.4k91kScience

Google DeepMind

Science Skills

70
Google DeepMind

jaspar-database

Query the JASPAR database for Transcription Factor (TF) binding profiles. Use when retrieving Position Frequency Matrices (PFMs) or Position Weight Matrices (PWMs) for specific TFs…

3.4k91kScience

Google DeepMind

Science Skills

70
Google DeepMind

literature-search-arxiv

Search for scientific papers, preprints, and publications on arXiv. Extract metadata, abstracts, and download full-text PDFs or HTML versions of papers. Use when the user asks to find…

3.4k91kResearch

Google DeepMind

Science Skills

70
Google DeepMind

pymol

Visualize, analyze, and render protein and molecular structures using PyMOL. Use when the user wants to create images of protein structures, perform structural alignments or superposition…

3.4k91kScience

wanshuiyin

Auto Claude Code Research In Sleep

68
wanshuiyin

analyze-results

Analyze ML experiment results, compute statistics, generate comparison tables and insights. Use when user says "analyze results", "compare", or needs to interpret experimental data.

19k42kResearch

Google DeepMind

Science Skills

68
Google DeepMind

gnomad-database

Query the Genome Aggregation Database (gnomAD). Use when determining the rarity or allele frequency of specific genetic variants, retrieving gene constraint metrics (pLI, LOEUF) to assess…

3.4k91kBackend

Google DeepMind

Science Skills

68
Google DeepMind

string-database

Query the STRING database for protein-protein interactions (PPIs), functional enrichment, and homology. Use when the user asks about interactions between specific proteins, interaction…

3.4k91kBackend

Google DeepMind

Science Skills

66
Google DeepMind

credentials

Instructions for handling API keys and credentials safely, verifying their presence, and prompting the user to add them if missing using a safe protocol.

3.4k91kScience

Google DeepMind

Science Skills

63
Google DeepMind

uv

Checks whether the uv Python package manager is installed and installs it if missing. Ensures uv is on PATH. Use when another skill requires uv as a prerequisite.

3.4k91kScience

GarethManning

Education Agent Skills

61
GarethManning

cognitive-tutoring-architecture-designer

Map knowledge components and skill hierarchies for a cognitive tutoring system or adaptive learning platform. Use when designing intelligent tutoring software or skill-based mastery systems.

97125kEducation

GarethManning

Education Agent Skills

61
GarethManning

digital-worked-example-sequence

Create an interactive digital worked example sequence with fading for online or blended delivery. Use when building e-learning modules, LMS content, or app-based instruction.

97125kEducation

Science skills, explained.

Also searched as: scientific agent skills, bioinformatics skill, ai scientist skills, deepmind science skills.

What are the best Claude skills for science?

Right now the top-ranked science skills on Alyn are Arize Evaluator (GitHub), Arize Experiment (GitHub), Caveman Manage (JuliusBrussee). Rankings combine GitHub stars, installs, freshness and depth, and update live.

Are there official DeepMind skills?

Yes. google-deepmind/science-skills is published by Google DeepMind for agentic scientific workflows.

Do science skills replace domain review?

No. They speed up analysis; results still need expert review.

How do I install a science skill?

Run npx skills add owner/repo in your project, or copy the folder with SKILL.md into ~/.claude/skills. Every skill on this page has a ready-to-copy command.

Built a science skill? Get it ranked.

Submit a skill