Best Claude skills for science
Science skills give agents domain tools for biology, chemistry, genomics and physics: database lookups, analysis pipelines and lab workflows. K-Dense's scientific-agent-skills and Google DeepMind's science-skills are the largest collections.
117 science skills · ranked live · November 2026
The top 10. Ranked by the Alyn Score.
- 1#1
GitHub
Awesome Copilot
GitHub
Arize Evaluator
Handles LLM-as-judge evaluation workflows on Arize including creating/updating evaluators, running evaluations on spans or experiments, managing tasks, trigger-run operations, column…
41k2.4MScore 85 - 2#2
GitHub
Awesome Copilot
GitHub
Arize Experiment
Creates, runs, and analyzes Arize experiments for evaluating and comparing model performance. Covers experiment CRUD, exporting runs, comparing results, and evaluation workflows using the…
41k2.4MScore 85 - 3#3

JuliusBrussee
Caveman Manage
Inspect Caveman Cloud's experiment lifecycle and block unsafe execution. Use when asked to start, approve, cancel, promote or roll back a Caveman experiment.
119k4.8MScore 85 - 4#4
K-Dense
Scientific Agent Skills
K-Dense
Alphagenome
Looks up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq…
57k328kScore 84 - 5#5
K-Dense
Scientific Agent Skills
K-Dense
Analytical Method Validation
Plans, executes, and documents validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP //, ICH M10 bioanalytical, CLSI EP, or…
57k328kScore 84 - 6#6
K-Dense
Scientific Agent Skills
K-Dense
Arbor
Applies Arbor Hypothesis Tree Refinement to research artifacts with repeatable evaluators, including model training, agent harnesses, data synthesis and benchmark optimization. Uses…
57k328kScore 84 - 7#7
sickn33
Agentic Awesome Skills
sickn33
Ab Testing
When the user wants to plan, design, or implement an A/B test or experiment, or build a growth experimentation program.
49k584kScore 83 - 8#8
GitHub
Awesome Copilot
GitHub
Autoresearch
Autonomous iterative experimentation loop for any programming task. Guides the user through defining goals, measurable metrics, and scope constraints, then runs an autonomous loop of code…
41k2.4MScore 83 - 9#9

davila7
Data Scientist
Expert data scientist for advanced analytics, machine learning, and statistical modeling. Handles complex data analysis, predictive modeling, and business intelligence.
33k285kScore 78 - 10#10
Jeffallan
Claude Skills
Jeffallan
Chaos Engineer
Designs chaos experiments, creates failure injection frameworks, and facilitates game day exercises for distributed systems — producing runbooks, experiment manifests, rollback procedures…
12k457kScore 77
What makes a great science skill.
Pinned, real libraries and databases with usage examples.
Validation steps that catch silent errors in pipelines.
Clear licensing for data sources.
All 117 science skills.
wanshuiyin
Auto Claude Code Research In Sleep
experiment-plan
Turn a refined research proposal or method idea into a detailed, claim-driven experiment roadmap. Use after `research-refine`, or when the user asks for a detailed experiment plan, ablation…
Google DeepMind
Science Skills
gtex-database
Use when you want to retrieve quantitative RNA expression data and variant eQTL information from the GTEx (Genotype-Tissue Expression) Project across 54 non-diseased tissue sites.
Google DeepMind
Science Skills
human-protein-atlas-database
Use when you want to retrieve semi-quantitative protein expression and spatial localisation data from the Human Protein Atlas (HPA).
Google DeepMind
Science Skills
interpro-database
Identify domains, families, and sites in proteins; find all proteins in a family or sharing a domain; explore species distribution for a domain; annotate genomes with protein families and…
Google DeepMind
Science Skills
literature-search-biorxiv
Browse and filter life sciences, biology, and medical preprints from bioRxiv and medRxiv. Supports fetching paper metadata by DOI, and browsing by date range with category and keyword…
Google DeepMind
Science Skills
literature-search-europepmc
Search Europe PMC for scientific literature and download open-access full texts and PDFs. Retrieve full-text XML/plain text by PMCID, get citation lists and bibliography.
Google DeepMind
Science Skills
literature-search-openalex
Query the OpenAlex scholarly database for research papers, authors, institutions, topics, sources, publishers, funders, geo-locations, and keywords. Use when searching academic papers…
Google DeepMind
Science Skills
ncbi-sequence-fetch
Retrieve protein and nucleotide sequences from NCBI databases using E-utilities. Supports direct accession lookup, CDS translation, gene+organism search, locus lookup, PubMed-linked…
Google DeepMind
Science Skills
openfda-database
Query, search, and download data from the openFDA API for drugs, devices, foods, tobacco, cosmetics, animal and veterinary products, substances, and transparency data. Use for FDA adverse…
Google DeepMind
Science Skills
opentargets-database
Query Open Targets Platform for target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs, for therapeutic target identification.
Google DeepMind
Science Skills
pdb-database
Use when you want to search for or download experimentally-determined 3D structures for biomolecules (proteins, nucleic acids, bound ligands). Supports searching by sequence similarity…
Google DeepMind
Science Skills
predictingthepast
Ancient text restoration, attribution, dating, contextualization, and embedding via Aeneas (Latin) / Ithaca (Ancient Greek). Use when asked to "restore", "attribute", "date"…
Google DeepMind
Science Skills
protein-sequence-similarity-search
Searches for homologous protein sequences using MMseqs2 (fast, default) or BLAST (comprehensive, fallback). Trigger this whenever the user provides a protein sequence or FASTA file and asks…
Google DeepMind
Science Skills
pubmed-database
Search PubMed for scientific literature, including published clinical trials. Fetch abstracts and full text. Link published research to biological databases (gene, protein, nucleotide…
Google DeepMind
Science Skills
reactome-database
Query the Reactome database (Analysis and Content Services). Use when the user asks about pathway analysis, gene list enrichment, retrieving results by token, finding unmapped or not-found…
Google DeepMind
Science Skills
ucsc-conservation-and-tfbs
Fetch Evolutionary Conservation scores (phyloP, phastCons) and Transcription Factor Binding Sites (TFBS) from the UCSC Genome Browser. Use when analyzing whether genomic variants or regions…
Google DeepMind
Science Skills
uniprot-database
Access protein metadata, function, taxonomy, and sequences across UniProtKB, UniParc, and UniRef. Use when searching for proteins, mapping identifiers, or retrieving functional annotations…
Google DeepMind
Science Skills
workflow-skill-creator
Distills a completed user workflow or interaction into a reusable agent skill. Use when the user asks to turn their workflow, interaction, or multi-step process into a skill, or when they…
Google DeepMind
Science Skills
foldseek-structural-search
Performs 3D structural searches of proteins against various databases (PDB, AlphaFold, CATH, MGnify, etc.) using the Foldseek API. Use ONLY when the user provides a physical 3D coordinate…
Google DeepMind
Science Skills
protein-sequence-msa
Performs multiple sequence alignment of proteins with EBI Clustal Omega. Use when you need to align multiple sequences to assess similarity, domain conservation, or key residue…
Google DeepMind
Science Skills
pubchem-database
Query PubChem, search by name/CID/SMILES, retrieve properties, similarity/substructure searches, bioactivity, for cheminformatics. Use when a user asks about a specific chemical, drug, or…
Google DeepMind
Science Skills
quickgo-database
Query the QuickGO and Evidence & Conclusion Ontology (ECO) REST API. Use this when you need to map genes to biological processes, molecular functions, or cellular components, find genes…
Google DeepMind
Science Skills
unibind-database
Queries the UniBind database for experimentally validated transcription factor (TF) binding sites. Use when retrieving direct TF-DNA interaction datasets, downloading binding site…
Google DeepMind
Science Skills
alphafold-database-fetch-and-analyze
Retrieve and analyze AlphaFold predicted structures for a protein. Use when the user provides a specific UniProt Accession ID and wants structural confidence metrics (pLDDT), domain…
Google DeepMind
Science Skills
alphagenome-atlas-website-links
Constructs deep-links and URLs for the AlphaGenome Atlas website. Supports generating single-variant exploration links (1-based VCF-style coordinates), genomic locus views (1-based closed…
Google DeepMind
Science Skills
alphagenome-variant-impact-score
Score, annotate, and analyze the functional impact of genetic variants using AlphaGenome Variant Impact (AVI) scores. Query variants in chr:pos:ref>alt format, annotate VCF/tabular…
Google DeepMind
Science Skills
jaspar-database
Query the JASPAR database for Transcription Factor (TF) binding profiles. Use when retrieving Position Frequency Matrices (PFMs) or Position Weight Matrices (PWMs) for specific TFs…
Google DeepMind
Science Skills
literature-search-arxiv
Search for scientific papers, preprints, and publications on arXiv. Extract metadata, abstracts, and download full-text PDFs or HTML versions of papers. Use when the user asks to find…
Google DeepMind
Science Skills
pymol
Visualize, analyze, and render protein and molecular structures using PyMOL. Use when the user wants to create images of protein structures, perform structural alignments or superposition…
wanshuiyin
Auto Claude Code Research In Sleep
analyze-results
Analyze ML experiment results, compute statistics, generate comparison tables and insights. Use when user says "analyze results", "compare", or needs to interpret experimental data.
Google DeepMind
Science Skills
gnomad-database
Query the Genome Aggregation Database (gnomAD). Use when determining the rarity or allele frequency of specific genetic variants, retrieving gene constraint metrics (pLI, LOEUF) to assess…
Google DeepMind
Science Skills
string-database
Query the STRING database for protein-protein interactions (PPIs), functional enrichment, and homology. Use when the user asks about interactions between specific proteins, interaction…
Google DeepMind
Science Skills
credentials
Instructions for handling API keys and credentials safely, verifying their presence, and prompting the user to add them if missing using a safe protocol.
Google DeepMind
Science Skills
uv
Checks whether the uv Python package manager is installed and installs it if missing. Ensures uv is on PATH. Use when another skill requires uv as a prerequisite.
GarethManning
Education Agent Skills
cognitive-tutoring-architecture-designer
Map knowledge components and skill hierarchies for a cognitive tutoring system or adaptive learning platform. Use when designing intelligent tutoring software or skill-based mastery systems.
GarethManning
Education Agent Skills
digital-worked-example-sequence
Create an interactive digital worked example sequence with fading for online or blended delivery. Use when building e-learning modules, LMS content, or app-based instruction.
Science skills, explained.
Also searched as: scientific agent skills, bioinformatics skill, ai scientist skills, deepmind science skills.
What are the best Claude skills for science?
Right now the top-ranked science skills on Alyn are Arize Evaluator (GitHub), Arize Experiment (GitHub), Caveman Manage (JuliusBrussee). Rankings combine GitHub stars, installs, freshness and depth, and update live.
Are there official DeepMind skills?
Yes. google-deepmind/science-skills is published by Google DeepMind for agentic scientific workflows.
Do science skills replace domain review?
No. They speed up analysis; results still need expert review.
How do I install a science skill?
Run npx skills add owner/repo in your project, or copy the folder with SKILL.md into ~/.claude/skills. Every skill on this page has a ready-to-copy command.
More in Science & data
Science skills for your agent