Best Claude skills for science
Science skills give agents domain tools for biology, chemistry, genomics and physics: database lookups, analysis pipelines and lab workflows. K-Dense's scientific-agent-skills and Google DeepMind's science-skills are the largest collections.
117 science skills · ranked live · November 2026
The top 10. Ranked by the Alyn Score.
- 1#1
GitHub
Awesome Copilot
GitHub
Arize Evaluator
Handles LLM-as-judge evaluation workflows on Arize including creating/updating evaluators, running evaluations on spans or experiments, managing tasks, trigger-run operations, column…
41k2.4MScore 85 - 2#2
GitHub
Awesome Copilot
Arize Experiment
Creates, runs, and analyzes Arize experiments for evaluating and comparing model performance. Covers experiment CRUD, exporting runs, comparing results, and evaluation workflows using the…
41k2.4MScore 85 - 3#3
JuliusBrussee
Caveman Manage
Inspect Caveman Cloud's experiment lifecycle and block unsafe execution. Use when asked to start, approve, cancel, promote or roll back a Caveman experiment.
119k4.8MScore 85 - 4#4
K-Dense
Scientific Agent Skills
K-Dense
Alphagenome
Looks up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq…
57k328kScore 84 - 5#5
K-Dense
Scientific Agent Skills
Analytical Method Validation
Plans, executes, and documents validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP //, ICH M10 bioanalytical, CLSI EP, or…
57k328kScore 84 - 6#6
K-Dense
Scientific Agent Skills
Arbor
Applies Arbor Hypothesis Tree Refinement to research artifacts with repeatable evaluators, including model training, agent harnesses, data synthesis and benchmark optimization. Uses…
57k328kScore 84 - 7#7
sickn33
Agentic Awesome Skills
sickn33
Ab Testing
When the user wants to plan, design, or implement an A/B test or experiment, or build a growth experimentation program.
49k584kScore 83 - 8#8
GitHub
Awesome Copilot
Autoresearch
Autonomous iterative experimentation loop for any programming task. Guides the user through defining goals, measurable metrics, and scope constraints, then runs an autonomous loop of code…
41k2.4MScore 83 - 9#9
davila7
Data Scientist
Expert data scientist for advanced analytics, machine learning, and statistical modeling. Handles complex data analysis, predictive modeling, and business intelligence.
33k285kScore 78 - 10#10
Jeffallan
Claude Skills
Jeffallan
Chaos Engineer
Designs chaos experiments, creates failure injection frameworks, and facilitates game day exercises for distributed systems — producing runbooks, experiment manifests, rollback procedures…
12k457kScore 77
What makes a great science skill.
Pinned, real libraries and databases with usage examples.
Validation steps that catch silent errors in pipelines.
Clear licensing for data sources.
All 117 science skills.
K-Dense
Scientific Agent Skills
K-Densecellprofiler
Runs reproducible CellProfiler microscopy pipelines for nuclear segmentation, cell counts, and per-object fluorescence measurements. Supports image/channel manifests, headless batch…
K-Dense
Scientific Agent Skills
K-Densecitation-management
Comprehensive citation management for academic research. Search OpenAlex, PubMed, and Google Scholar for papers, extract accurate metadata, validate citations, and generate properly…
K-Dense
Scientific Agent Skills
K-Denseclinical-decision-support
Prepares and validates research-only clinical decision-support evaluation, evidence-profile, cohort, survival, biomarker/model, privacy, and governance artifacts. Supports aggregate or…
K-Dense
Scientific Agent Skills
K-Denseclinical-reports
Creates safety-bounded draft structures and runs local deterministic checks for clinical case, diagnostic, trial, safety, and aggregate research reports. Use only with synthetic…
K-Dense
Scientific Agent Skills
K-Densedeepchem
Builds molecular property prediction and MoleculeNet workflows with DeepChem, including SMILES featurization, scaffold or grouped holdouts, masked labels, graph models and explicit…
K-Dense
Scientific Agent Skills
K-Densedeeptools
NGS analysis toolkit. BAM to bigWig conversion, QC (correlation, PCA, fingerprints), heatmaps/profiles (TSS, peaks), for ChIP-seq, RNA-seq, ATAC-seq visualization.
K-Dense
Scientific Agent Skills
K-Densedepmap
Retrieves and analyzes Cancer Dependency Map (DepMap) release data, including CRISPR Chronos gene effects, cancer model annotations, omics biomarkers, and PRISM drug sensitivity. Supports…
K-Dense
Scientific Agent Skills
K-Densediffdock
Predicts protein-small-molecule binding poses with DiffDock and DiffDock-L from PDB or sequence plus SMILES/SDF/MOL2. Covers batch docking, pose triage, confidence interpretation, and…
K-Dense
Scientific Agent Skills
K-Densednanexus-integration
Builds and operates reproducible genomics workloads on DNAnexus with the dx CLI, dxpy, apps/applets, native workflows, dxCompiler, and Nextflow. Supports DNAnexus data transfers, dxapp.json…
K-Dense
Scientific Agent Skills
K-Denseesm
Uses the Biohub esm Python SDK for ESM3 protein generation, ESMC embeddings, and ESMFold2 all-atom folding. Applies to local model inference and Biohub hosted clients, including former…
K-Dense
Scientific Agent Skills
K-Denseetetoolkit
Analyzes, manipulates, compares, annotates, and visualizes phylogenetic or other hierarchical trees with ETE 4. Supports Newick/Nexus tree I/O, topology edits and pattern matching…
K-Dense
Scientific Agent Skills
K-Denseexa-search
Searches scientific and technical web content with Exa and extracts page or PDF text from URLs in batches. Supports scholarly discovery with the publication category and academic domain…
K-Dense
Scientific Agent Skills
K-Denseexperimental-design
Designs experiments and studies BEFORE data is collected — choosing a design, randomizing, blocking, and laying out treatment combinations so results are interpretable. Use whenever someone…
K-Dense
Scientific Agent Skills
K-Denseexploratory-data-analysis
Performs bounded, local exploratory analysis of explicitly supported scientific files. Supports redacted CSV/TSV/JSON profiles; optional NumPy, HDF5, FASTA/FASTQ, and basic image metadata…
K-Dense
Scientific Agent Skills
K-Denseadaptyv
Uses the Adaptyv Bio Foundry API and Python SDK to design protein characterization experiments, estimate costs, submit sequences, monitor laboratory progress, and retrieve results. Applies…
K-Dense
Scientific Agent Skills
K-Denseaeon
This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use…
K-Dense
Scientific Agent Skills
K-Denseanndata
Handles annotated matrices in single-cell analysis, .h5ad and Zarr files, and integration with the scverse ecosystem. This is the data format skill—for analysis workflows use scanpy; for…
K-Dense
Scientific Agent Skills
K-Denseastropy
Core Python library for astronomy and astrophysics workflows that need Astropy APIs, including units/quantities, coordinates, FITS I/O, tables, time systems, WCS, and cosmology. Use when…
K-Dense
Scientific Agent Skills
K-Densebenchling-integration
Benchling Python SDK and REST API integration for registry entities, inventory, ELN entries, workflows, Benchling Apps, and Data Warehouse queries. Use when automating lab data with…
K-Dense
Scientific Agent Skills
K-Densebiopython
Provides Biopython workflows for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez). Supports batch processing, custom…
K-Dense
Scientific Agent Skills
K-Densecellxgene-census
Queries the CZ CELLxGENE Census programmatically for versioned public single-cell and spatial transcriptomics data. Use when you need population-scale cell metadata, gene expression slices…
K-Dense
Scientific Agent Skills
K-Densecirq
Google quantum computing framework. Use when targeting Google Quantum AI hardware, designing noise-aware circuits, or running quantum characterization experiments. Best for Google hardware…
K-Dense
Scientific Agent Skills
K-Densecobrapy
Performs constraint-based metabolic modeling with COBRApy, including FBA, pFBA, FVA, gene knockouts, flux sampling, growth media, production envelopes, gap filling, and SBML model…
K-Dense
Scientific Agent Skills
K-Denseconsciousness-council
Structures a multi-perspective council exercise for decisions, research trade-offs, and creative challenges. Simulates thinking archetypes, separates evidence from assumptions and values…
K-Dense
Scientific Agent Skills
K-Densedask
Scales pandas, NumPy, and custom Python research workflows beyond memory or across clusters with Dask. Covers DataFrames, Arrays, Bags, Futures, chunking, schedulers, and distributed…
K-Dense
Scientific Agent Skills
K-Densedatabase-lookup
Queries documented public database APIs with explicit endpoints, filters, pagination, and provenance. Used when a scientific, regulatory, financial, or other database-backed fact must be…
K-Dense
Scientific Agent Skills
K-Densedatalad
Retrieves, versions, and publishes scientific datasets with DataLad and git-annex, and captures computational provenance with datalad run, rerun, and containers-run. Use when cloning or…
K-Dense
Scientific Agent Skills
K-Densedatamol
Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery including SMILES parsing, standardization, descriptors, fingerprints…
K-Dense
Scientific Agent Skills
K-Densedeepspot-m
Generates transcriptome-wide virtual spatial transcriptomics from H&E histology with DeepSpot-M. Used for predicted log1p-CPM expression from 224x224 tiles at about 20x, querying the…
K-Dense
Scientific Agent Skills
K-Densedhdna-profiler
Applies the DHDNA framework as an exploratory rubric for reasoning and writing patterns in supplied text. Used for explicit requests for DHDNA, cognitive-style reflection, a…
K-Dense
Scientific Agent Skills
K-Densebgpt-paper-search
Searches BGPT scientific papers by topic or DOI and retrieves claim-level evidence extracted from full text, including experiments, reported statistics, scope, limitations, and provenance…
Google DeepMind
Science Skills
Google DeepMindclinvar-database
Use when needing clinical significance, pathogenicity classifications (e.g., Pathogenic, Benign, VUS), clinical evidence rationales, or finding "hard positive" benchmark controls for human…
Google DeepMind
Science Skills
Google DeepMinddbsnp-database
Use when you want to look up, map, and search for short genetic variants (SNPs, indels) in NCBI's dbSNP database. Resolves between rsIDs, genomic coordinates in VCF format, and HGVS…
Google DeepMind
Science Skills
Google DeepMindembl-ebi-ols
Query and search the EMBL-EBI Ontology Lookup Service (OLS) for biomedical ontology terms, definitions, and hierarchies across 250+ ontologies (e.g., GO, DOID, HP). Use when the user asks…
Google DeepMind
Science Skills
Google DeepMindencode-ccres-database
Query the ENCODE Registry of cis-Regulatory Elements (cCREs) via the SCREEN GraphQL API, or make custom queries to the ENCODE Portal REST API for experiments and files (ChIP-seq peaks…
Google DeepMind
Science Skills
Google DeepMindensembl-database
Query the Ensembl database to resolve gene, transcript, and protein IDs, fetch genomic or protein sequences, retrieve gene structures (exons), and get variant consequence and effect…
Science skills, explained.
Also searched as: scientific agent skills, bioinformatics skill, ai scientist skills, deepmind science skills.
What are the best Claude skills for science?
Right now the top-ranked science skills on Alyn are Arize Evaluator (GitHub), Arize Experiment (GitHub), Caveman Manage (JuliusBrussee). Rankings combine GitHub stars, installs, freshness and depth, and update live.
Are there official DeepMind skills?
Yes. google-deepmind/science-skills is published by Google DeepMind for agentic scientific workflows.
Do science skills replace domain review?
No. They speed up analysis; results still need expert review.
How do I install a science skill?
Run npx skills add owner/repo in your project, or copy the folder with SKILL.md into ~/.claude/skills. Every skill on this page has a ready-to-copy command.
More in Science & data
Science skills for your agent